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| Content Provider | PubMed Central |
|---|---|
| Author | Jain, Sachin Choudhary, Gajendra Pratap Jain, Dinesh Kumar |
| Copyright Year | 2013 |
| Abstract | Objectives. Pharmacological and antifertility activity evaluation of Jatropha gossypifolia in rats. Methods. The antifertility activity of the extracts of Jatropha gossypifolia in rats was evaluated using two experimental animal models. Estrogenic activity was evaluated in immature female rats using ethinyl estradiol as standard. Anti-implantation and early abortifacient activity was performed in female Wistar rats by determining the number of implantations and implantation resorptions. Results. In estrogenic activity evaluations, the ethanolic and aqueous extracts offered significant estrogen-like activity at 400 mg kg−1 p.o. by increasing the uterine weight compared to vehicle control group. Ethanolic extract (400 mg kg−1, p.o.) treatment significantly decreased the number of implants and increased the number of resorptions compared to vehicle control group. Conclusion. The results of the present study provide the evidence of the anti-fertility activity of Jatropha gossypifolia as claimed in the traditional use. The results are consistent with the literature reports related to the antifertility effect of flower extracts of Jatropha gossypifolia. |
| Related Links | http://dx.doi.org/10.1155/2013/125980 |
| Starting Page | 125980 |
| File Format | |
| ISSN | 23146133 |
| e-ISSN | 23146141 |
| Journal | BioMed Research International |
| Volume Number | 2013 |
| Language | English |
| Publisher | Hindawi Publishing Corporation |
| Publisher Date | 2013-01-01 |
| Access Restriction | Open |
| Rights Holder | Hindawi Publishing Corporation |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Microbiology Medicine Biochemistry, Genetics and Molecular Biology |
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