NDLI: ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes.

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Role of IME1 expression in regulation of meiosis in Saccharomyces cerevisiae.

Analysis of a gene cluster for sarcotoxin II, a group of antibacterial proteins of Sarcophaga peregrina.

A suppressor of an RNA polymerase II mutation of Saccharomyces cerevisiae encodes a subunit common to RNA polymerases I, II, and III.

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Interleukin-1-mediated enhancement of mouse factor B gene expression via NF kappa B-like hepatoma nuclear factor.

Angiotensin II stimulates protein-tyrosine phosphorylation in a calcium-dependent manner.

Effect of 5' splice site mutations on splicing of the preceding intron.

Multiple cis- and trans-acting elements involved in regulation of the neu gene.

cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases.

Interleukin-1 synergy with phosphoinositide pathway agonists for induction of interleukin-2 gene expression: molecular basis of costimulation.

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

Replication timing of DNA sequences associated with human centromeres and telomeres.

Induction of yeast histone genes by stimulation of stationary-phase cells.

Transcriptional derepression of the Saccharomyces cerevisiae HSP26 gene during heat shock.

Partial deletion of alpha satellite DNA associated with reduced amounts of the centromere protein CENP-B in a mitotically stable human chromosome rearrangement.

Complex transcription from the extrachromosomal DNA encoding mitochondrial functions of Plasmodium yoelii.

gcr2, a new mutation affecting glycolytic gene expression in Saccharomyces cerevisiae.

A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal.

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The SCL gene is formed from a transcriptionally complex locus.

The trypanosome leucine repeat gene in the variant surface glycoprotein expression site encodes a putative metal-binding domain and a region resembling protein-binding domains of yeast, Drosophila, and mammalian proteins.

A dominant negative mutation of the alpha retinoic acid receptor gene in a retinoic acid-nonresponsive embryonal carcinoma cell.

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A DNA-activated protein kinase from HeLa cell nuclei.

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Regulation of glucose transporters in LLC-PK1 cells: effects of D-glucose and monosaccharides.

Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae.

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Positive and negative transcriptional elements of the human type IV collagenase gene.

Identification of cis-acting regulatory elements in the promoter region of the rat brain creatine kinase gene.

Sequence and functional similarity between a yeast ribosomal protein and the Escherichia coli S5 ram protein.

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage.

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Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.

Hyperphosphorylation of the retinoblastoma gene product is determined by domains outside the simian virus 40 large-T-antigen-binding regions.

Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse.

Mechanism of estrogen receptor-dependent transcription in a cell-free system.

Characterization of nonconservative homologous junctions in mammalian cells.

Functional expression of the genomic DNA sequences encoding mouse Na,K-ATPase alpha 1 gene by cotransfection of overlapping genomic DNA segments.

Two adjacent C/EBP-binding sequences that participate in the cell-specific expression of the mouse serum amyloid A3 gene.

Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter.

Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family.

Expression of a gene family in the dimorphic fungus Mucor racemosus which exhibits striking similarity to human ras genes.

Activation of chromosomal vitellogenin genes in Xenopus oocytes by pure estrogen receptor and independent activation of albumin genes.

Serum stimulation of NIH 3T3 cells induces the production of lipids able to inhibit GTPase-activating protein activity.

ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes.

Regulation of N-myc gene expression: use of an adenovirus vector to demonstrate posttranscriptional control.

A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter.

Identification, characterization, and cell specificity of a human LINE-1 promoter.

Activation of a late H2B histone gene in blastula-stage sea urchin embryos by an unusual enhancer element located 3' of the gene.

Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae.

Germ line transmission of an inactive N-myc allele generated by homologous recombination in mouse embryonic stem cells.

Long insertions within telomeres contribute to chromosome size polymorphism in Plasmodium berghei.

Aryl hydrocarbon induction of rat cytochrome P-450d results from increased precursor RNA processing.

Pip92: a short-lived, growth factor-inducible protein in BALB/c 3T3 and PC12 cells.

A relative of the catalytic subunit of cyclic AMP-dependent protein kinase in Aplysia spermatozoa.

Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene.

Structural isoforms of a membrane transport protein from Leishmania enriettii.

Two related families of retrotransposons from Schizosaccharomyces pombe.

Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells.

Increased rate of base substitution in a hamster mutator strain obtained during serial selection for gene amplification.

The PRE and PQ box are functionally distinct yeast pheromone response elements.

Species-specific lens activation of the thymidine kinase promoter by a single copy of the mouse alpha A-CRYBP1 site and loss of tissue specificity by multimerization.

Regulated expression of the small nuclear ribonucleoprotein particle protein SmN in embryonic stem cell differentiation.

Cloning and Sequencing of a New gro Transcript from Activated Human Monocytes: Expression in Leukocytes and Wound Tissue

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ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes.

Content Provider	PubMed Central
Author	Stearns, T. Kahn, R. A. Botstein, D. Hoyt, M. A.
Abstract	ADP ribosylation factor (ARF) is a ubiquitous 21-kDa GTP-binding protein in eucaryotes. ARF was first identified in animal cells as the protein factor required for the efficient ADP-ribosylation of the mammalian G protein Gs by cholera toxin in vitro. A gene (ARF1) encoding a protein homologous to mammalian ARF was recently cloned from Saccharomyces cerevisiae (Sewell and Kahn, Proc. Natl. Acad. Sci. USA, 85:4620-4624, 1988). We have found a second gene encoding ARF in S. cerevisiae, ARF2. The two ARF genes are within 28 centimorgans of each other on chromosome IV, and the proteins encoded by them are 96% identical. Disruption of ARF1 causes slow growth, cold sensitivity, and sensitivity to normally sublethal concentrations of fluoride ion in the medium. Disruption of ARF2 causes no detectable phenotype. Disruption of both genes is lethal; thus, ARF is essential for mitotic growth. The ARF1 and ARF2 proteins are functionally homologous, and the phenotypic differences between mutations in the two genes can be accounted for by the level of expression; ARF1 produces approximately 90% of total ARF. Among revertants of the fluoride sensitivity of an arf1 null mutation were ARF1-ARF2 fusion genes created by a gene conversion event in which the deleted ARF1 sequences were repaired by recombination with ARF2.
Starting Page	6690
File Format	PDF
ISSN	10985549
e-ISSN	10985549
Journal	Molecular and Cellular Biology
Issue Number	12
Volume Number	10
Language	English
Publisher Date	1990-12-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Cell Biology Molecular Biology

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