NDLI: Reverse engineering the euglenoid movement

Content Provider	PubMed Central
Author	Arroyo, Marino Heltai, Luca Millán, Daniel Desimone, Antonio
Abstract	Euglenids exhibit an unconventional motility strategy amongst unicellular eukaryotes, consisting of large-amplitude highly concerted deformations of the entire body (euglenoid movement or metaboly). A plastic cell envelope called pellicle mediates these deformations. Unlike ciliary or flagellar motility, the biophysics of this mode is not well understood, including its efficiency and molecular machinery. We quantitatively examine video recordings of four euglenids executing such motions with statistical learning methods. This analysis reveals strokes of high uniformity in shape and pace. We then interpret the observations in the light of a theory for the pellicle kinematics, providing a precise understanding of the link between local actuation by pellicle shear and shape control. We systematically understand common observations, such as the helical conformations of the pellicle, and identify previously unnoticed features of metaboly. While two of our euglenids execute their stroke at constant body volume, the other two exhibit deviations of about 20% from their average volume, challenging current models of low Reynolds number locomotion. We find that the active pellicle shear deformations causing shape changes can reach 340%, and estimate the velocity of the molecular motors. Moreover, we find that metaboly accomplishes locomotion at hydrodynamic efficiencies comparable to those of ciliates and flagellates. Our results suggest new quantitative experiments, provide insight into the evolutionary history of euglenids, and suggest that the pellicle may serve as a model for engineered active surfaces with applications in microfluidics.
Related Links	http://dx.doi.org/10.1073/pnas.1213977109
Ending Page	17879
Page Count	6
Starting Page	17874
File Format	PDF
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	44
Volume Number	109
Language	English
Publisher	National Academy of Sciences
Publisher Date	2012-10-30
Access Restriction	Open
Rights Holder	National Academy of Sciences
Subject Keyword	General Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Reverse engineering the euglenoid movement.

Reverse engineering the cognitive brain

Understanding biology by reverse engineering the control

Reverse engineering the (β/α)8 barrel fold

Automated reverse engineering of nonlinear dynamical systems

Reverse wave propagation in the cochlea

EuMoBot: Replicating euglenoid movement in a soft robot

Reverse engineering gene networks using singular value decomposition and robust regression

Reverse engineering dynamic temporal models of biological processes and their relationships

Reverse engineering the euglenoid movement

Similar Documents

Reverse engineering the euglenoid movement.

Reverse engineering the cognitive brain

Understanding biology by reverse engineering the control

Reverse engineering the (β/α)8 barrel fold

Automated reverse engineering of nonlinear dynamical systems

Reverse wave propagation in the cochlea

EuMoBot: Replicating euglenoid movement in a soft robot

Reverse engineering gene networks using singular value decomposition and robust regression

Reverse engineering dynamic temporal models of biological processes and their relationships

Reverse engineering the euglenoid movement