NDLI: Parent, sibling and peer influences on smoking initiation, regular smoking and nicotine dependence. Results from a genetically informative design

Content Provider	PubMed Central
Author	Scherrer, Jeffrey F. Xian, Hong Pan, Hui Pergadia, Michele L. Madden, Pamela A. F. Grant, Julia D. Sartor, Carolyn E. Haber, Jon Randolph Jacob, Theodore Bucholz, Kathleen K.
Abstract	We sought to determine whether parenting, sibling and peer influences are associated with offspring ever smoking, regular smoking and nicotine dependence (ND) after controlling for familial factors. We used a twin-family design and data from structured diagnostic surveys of 1,919 biological offspring (age 12–32 years), 1,107 twin fathers, and 1,023 mothers. Offspring were classified into one of four familial risk groups based on twin fathers' and their co-twins' history of DSM-III-R nicotine dependence. Multivariate multinomial logistic regression was used to model familial risk, paternal and maternal parenting behavior and substance use, sibling substance use, and friend and school peer smoking, alcohol and drug use. Ever smoking was associated with increasing offspring age, white race, high maternal pressure to succeed in school, sibling drug use, and friend smoking, alcohol and drug use. Offspring regular smoking was associated with these same factors with additional contribution from maternal ND. Offspring ND was associated with increasing offspring age, male gender, biological parents divorce, high genetic risk from father and mother ND, maternal problem drinking, maternal rule inconsistency and sibling drug use, and friend smoking, alcohol and drug use. Friend smoking had the largest magnitude of association with offspring smoking. This effect remains after accounting for familial liability and numerous parent and sibling level effects. Smoking interventions may have greatest impact by targeting smoking prevention among peer groups in adolescent and young adult populations.
Related Links	http://dx.doi.org/10.1016/j.addbeh.2011.10.005
Ending Page	247
Page Count	8
Starting Page	240
File Format	PDF
ISSN	03064603
e-ISSN	18736327
Journal	Addictive Behaviors
Issue Number	3
Volume Number	37
Language	English
Publisher Date	2012-03-01
Access Restriction	Open
Subject Keyword	Toxicology Medicine (miscellaneous) Clinical Psychology Psychiatry and Mental health Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Toxicology Clinical Psychology Psychiatry and Mental Health

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