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| Content Provider | PubMed Central |
|---|---|
| Author | Han, Sang-wook Sriariyanun, Malinee Lee, Sang-won Sharma, Manoj Bahar, Ofir Bower, Zachary Ronald, Pamela C. |
| Editor | Chakravortty, Dipshikha |
| Copyright Year | 2011 |
| Abstract | The rice XA21 pattern recognition receptor binds a type I secreted sulfated peptide, called axYS22, derived from the Ax21 (activator of XA21-mediated immunity) protein. The conservation of Ax21 in all sequenced Xanthomonas spp. and closely related genera suggests that Ax21 serves a key biological function. Here we show that the predicted N-terminal sequence of Ax21 is cleaved prior to secretion outside the cell and that mature Ax21 serves as a quorum sensing (QS) factor in Xanthomonas oryzae pv. oryzae. Ax21-mediated QS controls motility, biofilm formation and virulence. We provide genetic evidence that the Xoo RaxH histidine kinase serves as the bacterial receptor for Ax21. This work establishes a critical role for small protein-mediated QS in a Gram-negative bacterium. |
| Related Links | http://dx.doi.org/10.1371/journal.pone.0029192 |
| Starting Page | 29192 |
| File Format | |
| ISSN | 19326203 |
| e-ISSN | 19326203 |
| Journal | PLoS ONE |
| Issue Number | 12 |
| Volume Number | 6 |
| Language | English |
| Publisher | Public Library of Science |
| Publisher Date | 2011-12-12 |
| Access Restriction | Open |
| Rights Holder | Public Library of Science |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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