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| Content Provider | PubMed Central |
|---|---|
| Author | Phifer, Justine Skelton, Kelly Weiss, Tamara Schwartz, Ann Wingo, Aliza Gillespie, Charles F. Sands, Lauren Saleem, Sayyar Bradley, Bekh Jovanovic, Tanja Ressler, Kerry |
| Copyright Year | 2011 |
| Abstract | The comorbidity of pain syndromes and trauma related syndromes has been shown to be high. However, there have been limited data, especially in civilian medical populations, on the role of trauma related disorders such as Post Traumatic Stress Disorder (PTSD) on chronic pain and pain medication use. We analyzed 647 general hospital patients in primary care and obstetrics and gynecological waiting rooms for the experience of trauma and PTSD related stress disorders. PTSD symptoms were found to be significantly positively correlated with pain ratings (r=.282, p<.001) and pain related function impairment (r=.303, p<.001). Those with a current PTSD diagnosis had significantly higher subjective pain and pain related-impairment ratings than those with no PTSD. Furthermore, those with a current diagnosis of PTSD were significantly more likely to have used opioid analgesics for pain control compared to those without a diagnosis of PTSD (χ2=8.98, p=.011). When analyzing the separate PTSD symptom subclusters, (re-experiencing, avoidance and hyper-arousal), all symptom clusters were significantly related to pain and pain-related impairment ratings, but only the avoidance cluster was significantly related to prior opioid pain medication use. We conclude that PTSD and trauma-related disorders are common in impoverished medical populations and that their presence should be examined in patients with pain syndromes. Furthermore, these data suggest that PTSD and pain may share a vulnerability pathway including the endogenous opioid neurotransmission systems. |
| Related Links | http://dx.doi.org/10.1016/j.pain.2011.04.019 |
| Ending Page | 2240 |
| Page Count | 8 |
| Starting Page | 2233 |
| File Format | |
| ISSN | 03043959 |
| e-ISSN | 18726623 |
| Journal | Pain |
| Issue Number | 10 |
| Volume Number | 152 |
| Language | English |
| Publisher Date | 2011-10-01 |
| Access Restriction | Open |
| Subject Keyword | Anesthesiology and Pain Medicine Pharmacology Neurology Clinical Neurology Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Neurology (clinical) Pharmacology Anesthesiology and Pain Medicine |
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