NDLI: ExDom: an integrated database for comparative analysis of the exon–intron structures of protein domains in eukaryotes

Content Provider	PubMed Central
Author	Bhasi, Ashwini Philip, Philge Manikandan, Vinu Senapathy, Periannan
Copyright Year	2008
Abstract	We have developed ExDom, a unique database for the comparative analysis of the exon–intron structures of 96 680 protein domains from seven eukaryotic organisms (Homo sapiens, Mus musculus, Bos taurus, Rattus norvegicus, Danio rerio, Gallus gallus and Arabidopsis thaliana). ExDom provides integrated access to exon-domain data through a sophisticated web interface which has the following analytical capabilities: (i) intergenomic and intragenomic comparative analysis of exon–intron structure of domains; (ii) color-coded graphical display of the domain architecture of proteins correlated with their corresponding exon-intron structures; (iii) graphical analysis of multiple sequence alignments of amino acid and coding nucleotide sequences of homologous protein domains from seven organisms; (iv) comparative graphical display of exon distributions within the tertiary structures of protein domains; and (v) visualization of exon–intron structures of alternative transcripts of a gene correlated to variations in the domain architecture of corresponding protein isoforms. These novel analytical features are highly suited for detailed investigations on the exon–intron structure of domains and make ExDom a powerful tool for exploring several key questions concerning the function, origin and evolution of genes and proteins. ExDom database is freely accessible at: http://66.170.16.154/ExDom/.
Related Links	http://dx.doi.org/10.1093/nar/gkn746
Starting Page	703
File Format	PDF
ISSN	03051048
e-ISSN	13624962
Journal	Nucleic Acids Research
Issue Number	Database issue
Volume Number	37
Language	English
Publisher	Oxford University Press
Publisher Date	2009-01-01
Access Restriction	Open
Rights Holder	Oxford University Press
Subject Keyword	Genetics Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Genetics

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

ExDom: an integrated database for comparative analysis of the exon–intron structures of protein domains in eukaryotes

EID: the Exon–Intron Database—an exhaustive database of protein-coding intron-containing genes

Exalign: a new method for comparative analysis of exon–intron gene structures

EID: the Exon–Intron Database—an exhaustive database of protein-coding intron-containing genes

ExInt: an Exon Intron Database

ExInt: an Exon/Intron database

Exalign: a new method for comparative analysis of exon–intron gene structures

Analysis of evolution of exon-intron structure of eukaryotic genes

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

ExDom: an integrated database for comparative analysis of the exon–intron structures of protein domains in eukaryotes

Similar Documents

ExDom: an integrated database for comparative analysis of the exon–intron structures of protein domains in eukaryotes

EID: the Exon–Intron Database—an exhaustive database of protein-coding intron-containing genes

Exalign: a new method for comparative analysis of exon–intron gene structures

EID: the Exon–Intron Database—an exhaustive database of protein-coding intron-containing genes

ExInt: an Exon Intron Database

ExInt: an Exon/Intron database

Exalign: a new method for comparative analysis of exon–intron gene structures

Analysis of evolution of exon-intron structure of eukaryotic genes

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

ExDom: an integrated database for comparative analysis of the exon–intron structures of protein domains in eukaryotes