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| Content Provider | PubMed Central |
|---|---|
| Author | Peri, Alessandro Ilaria, Cellai Benvenuti, Susanna Luciani, Paola Baglioni, Silvana Serio, Mario |
| Copyright Year | 2008 |
| Abstract | Neuroblastoma (NB) is the most common extracranial tumor in children and accounts for around 15% of all paediatric oncology deaths. The treatment of NB includes surgery, chemotherapy, and radiotherapy. Unfortunately, most children with NB present with advanced disease, and more than 60% of patients with high-risk features will have a poor prognosis despite intensive therapy. Agonists of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) have been shown to have pleiotropic effects, including antineoplastic effects. The studies that addressed the role and the possible mechanism(s) of action of PPARγ in NB cells are reviewed. |
| Related Links | http://dx.doi.org/10.1155/2008/917815 |
| Starting Page | 917815 |
| File Format | |
| ISSN | 16874757 |
| e-ISSN | 16874765 |
| Journal | PPAR Research |
| Volume Number | 2008 |
| Language | English |
| Publisher | Hindawi Publishing Corporation |
| Publisher Date | 2008-01-01 |
| Access Restriction | Open |
| Rights Holder | Hindawi Publishing Corporation |
| Subject Keyword | Pharmacology (medical) Drug Discovery Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Drug Discovery Pharmacology (medical) |
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