NDLI: Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix

Content Provider	PubMed Central
Author	Ueno, Morio Matsumura, Michiru Watanabe, Kiichi Nakamura, Takahiro Osakada, Fumitaka Takahashi, Masayo Kawasaki, Hiroshi Kinoshita, Shigeru Sasai, Yoshiki
Copyright Year	2006
Abstract	Here we report a human-derived material with potent inductive activity that selectively converts ES cells into neural tissues. Both mouse and human ES cells efficiently differentiate into neural precursors when cultured on the matrix components of the human amniotic membrane in serum-free medium [amniotic membrane matrix-based ES cell differentiation (AMED)]. AMED-induced neural tissues have regional characteristics (brainstem) similar to those induced by coculture with mouse PA6 stromal cells [a common method called stromal cell-derived inducing activity (SDIA) culture]. Like the SDIA culture, the AMED system is applicable to the in vitro generation of various CNS tissues, including dopaminergic neurons, motor neurons, and retinal pigment epithelium. In contrast to the SDIA method, which uses animal cells, the AMED culture uses a noncellular inductive material derived from an easily available human tissue; therefore, AMED should provide a more suitable and versatile system for generating a variety of neural tissues for clinical applications.
Related Links	http://dx.doi.org/10.1073/pnas.0600104103
Ending Page	9559
Page Count	6
Starting Page	9554
File Format	PDF
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	25
Volume Number	103
Language	English
Publisher	National Academy of Sciences
Publisher Date	2006-06-20
Access Restriction	Open
Rights Holder	National Academy of Sciences
Subject Keyword	General Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.

Functional reconstruction of rabbit corneal epithelium by human limbal cells cultured on amniotic membrane

Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis

Corrigendum: Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Phenotypic conversion of human mammary carcinoma cells by autocrine human growth hormone

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity

Decellularized human amniotic membrane scaffolds: influence on the biological behavior of dental pulp stem cells

A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells

Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix

Similar Documents

Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.

Functional reconstruction of rabbit corneal epithelium by human limbal cells cultured on amniotic membrane

Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis

Corrigendum: Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Phenotypic conversion of human mammary carcinoma cells by autocrine human growth hormone

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity

Decellularized human amniotic membrane scaffolds: influence on the biological behavior of dental pulp stem cells

A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells

Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix