NDLI: Passive protection of dogs against clinical disease due to Canine parvovirus-2 by specific antibody from chicken egg yolk

Content Provider	PubMed Central
Author	Nguyen, Sa Van Umeda, Kouji Yokoyama, Hideaki Tohya, Yukinobu Kodama, Yoshikatsu
Copyright Year	2006
Abstract	The protective effect of immunoglobulins derived from chicken egg yolk (IgY) against infection by Canine parvovirus 2 (CPV-2) was evaluated in 10 beagle dogs orally challenged with a strain of the virus. The 2-mo-old dogs were divided into 3 groups and treated with powders containing CPV-2 IgY or normal egg yolk for 7 d after the challenge. The 4 dogs receiving normal egg yolk (control group) demonstrated mild symptoms typical of CPV-2 infection, such as vomiting, diarrhea, and weight loss. No symptoms were observed by 16 d after challenge in the 3 dogs receiving 2 g of IgY powder. Of the 3 dogs receiving 0.5 g of IgY powder, 2 had clinical CPV-2 disease; however, the manifestations were less severe than in the control group. Furthermore, the IgY-treated groups had significantly greater weight gain and shorter duration of virus shedding than the control group. These results indicate that IgY is useful in protecting dogs from CPV-2-induced clinical disease.
Starting Page	62
File Format	PDF
ISSN	08309000
Journal	Canadian Journal of Veterinary Research
Issue Number	1
Volume Number	70
Language	English
Publisher	Canadian Veterinary Medical Association
Publisher Date	2006-01-01
Access Restriction	Open
Rights Holder	Canadian Veterinary Medical Association
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Veterinary Medicine

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Passive protection of dogs against clinical disease due to Canine parvovirus-2 by specific antibody from chicken egg yolk