NDLI: Relapsed Babesia microti Infection Following Allogeneic Hematopoietic Cell Transplantation in a Patient With B-cell Acute Lymphoblastic Leukemia: Case Report and Review of the Literature

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Relapsed Babesia microti Infection Following Allogeneic Hematopoietic Cell Transplantation in a Patient With B-cell Acute Lymphoblastic Leukemia: Case Report and Review of the Literature

Content Provider	Oxford Academic
Author	Rosenblatt, Joshua Leung, Annie Baneman, Emily Fuller, Risa Taimur, Sarah Paniz-Mondolfi, Alberto E Malone, Adriana K Kirkman, Laura Jacobs, Samantha E
Copyright Year	2021
Abstract	A patient with relapsed/refractory B-cell acute lymphoblastic leukemia developed babesiosis before allogeneic hematopoietic cell transplantation while on atovaquone for Pneumocystis jirovecii pneumonia prophylaxis. Despite receiving a prolonged course of atovaquone and azithromycin until whole-blood Babesia microti DNA was no longer detected by polymerase chain reaction, her post-transplant course was complicated by relapsed babesiosis. We investigate the potential host and parasite characteristics causing relapsing/persistent infection.
Related Links	https://academic.oup.com/ofid/article-pdf/8/9/ofab323/40302982/ofab323.pdf
File Format	PDF
e-ISSN	23288957
DOI	10.1093/ofid/ofab323
Journal	Open Forum Infectious Diseases
Issue Number	9
Volume Number	8
Language	English
Publisher	Oxford Academic
Publisher Date	2021-09-01
Access Restriction	Open
Subject Keyword	Clinical Medicine Infectious Diseases Medicine and Health Polymerase Chain Reaction Azithromycin Atovaquone Burkitt's Lymphoma Hematopoietic Stem Cell Transplantation Babesiosis Leukemia, B-cell, Acute Infections Babesia Microti Persistence Parasites Transplantation Prevention Immunocompromised Host Ticks Whole Blood Hematopoietic Cell Transplantation Tick-borne Pathogens
Content Type	Text
Resource Type	Article
Subject	Oncology Infectious Diseases

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