NDLI: Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features

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Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features

Content Provider	MDPI
Author	Corrado, Inì Palmucci, Stefano Cosentino, Salvatore Fanzone, Luigi Pietro, Stefano Di Mari, Alessia Di Galioto, Federica Tiralongo, Francesco Vignigni, Giovanna Toscano, Stefano Sambataro, Gianluca Vancheri, Carlo Distefano, Giulio Basile, Antonio
Copyright Year	2021
Description	Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung is commonly involved in systemic vasculitides, with heterogeneous clinical, radiological, and histopathological presentations. Primary vasculitides most commonly associated with lung parenchymal involvement include small-vessel antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides, such as granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). Several studies have reported cases of interstitial lung diseases (ILDs) associated with systemic vasculitis, particularly those positive for ANCA associated vasculitis/vasculitidis: AAV. We have selected from our case series different radiological features of pulmonary vasculitis (i.e., solitary or multiple nodules, cavitary lesions, nodules with centrilobular or peribronchial distribution, airspace consolidations, “crazy paving” appearance, interstitial disease), including cases with interstitial lung alterations. Therefore, the aim of this review is to describe the typical clinical manifestations of vasculitides and their main radiologic features (especially AAV).
Starting Page	2318
e-ISSN	20754418
DOI	10.3390/diagnostics11122318
Journal	Diagnostics
Issue Number	12
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2021-12-09
Access Restriction	Open
Subject Keyword	Diagnostics Respiratory System Vasculitis Antibodies Antineutrophil Cytoplasmic Multidetector Computed Tomography Lung Diseases Interstitial
Content Type	Text
Resource Type	Article

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