NDLI: Dietary Patterns and Their Associations with Intermediate Age-Related Macular Degeneration in a Japanese Population

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Dietary Patterns and Their Associations with Intermediate Age-Related Macular Degeneration in a Japanese Population

Content Provider	MDPI
Author	Sasaki, Mariko Miyagawa, Naoko Harada, Sei Tsubota, Kazuo Takebayashi, Toru Nishiwaki, Yuji Kawasaki, Ryo
Copyright Year	2022
Description	This population-based cross-sectional study investigated the influence of dietary patterns on age-related macular degeneration (AMD) in a Japanese population. The Tsuruoka Metabolomics Cohort Study enrolled a general population aged 35–74 years from among participants in annual health check-up programs in Tsuruoka City, Japan. Eating habits were assessed using a food frequency questionnaire. Principal component analysis was used to identify dietary patterns among food items. The association between quartiles of scores for each dietary pattern and intermediate AMD was assessed using multivariate logistic regression models. Of 3433 participants, 415 had intermediate AMD. We identified four principal components comprising the Vegetable-rich pattern, Varied staple food pattern, Animal-rich pattern, and Seafood-rich pattern. After adjusting for potential confounders, higher Varied staple food diet scores were associated with a lower prevalence of intermediate AMD (fourth vs. first quartile) (OR, 0.63; 95% confidence interval [CI], 0.46–0.86). A significant trend of decreasing ORs for intermediate AMD associated with increasing Varied staple food diet scores was noted (p for trend = 0.002). There was no significant association between the other dietary patterns and intermediate AMD. In a Japanese population, individuals with a dietary pattern score high in the Varied staple food pattern had a lower prevalence of intermediate AMD.
Starting Page	1617
e-ISSN	20770383
DOI	10.3390/jcm11061617
Journal	Journal of clinical medicine
Issue Number	6
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2022-03-15
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Ophthalmology Age-related Macular Degeneration (amd) Intermediate Amd Dietary Pattern Principal Component Analysis Asian Staple Food
Content Type	Text
Resource Type	Article

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