Loading...
Please wait, while we are loading the content...
Similar Documents
Seroprevalence of Anti-SARS-CoV-2 Antibodies in Blood Donors from Nuevo Leon State, Mexico, during 2020: A Retrospective Cross-Sectional Evaluation
| Content Provider | MDPI |
|---|---|
| Author | Natalia, Martinez-Acuña Consuelo, Treviño-Garza Manuel, De-La-O-Cavazos Avalos-Nolazco, Diana Rodriguez-Rodriguez, Diana Martinez-Liu, Cynthia Galan-Huerta, Kame Padilla-Rivas, Gerardo Ramos-Jimenez, Javier La-Cruz, Sergio Ayala-De- Cienfuegos-Pecina, Eduardo Diaz-Chuc, Erik Cazares-Tamez, Rogelio Flores-Arechiga, Amador Perez-Chavez, Fernando Arellanos-Soto, Daniel Lozano-Sepulveda, Sonia Garza-Gonzalez, Elvira Oca-Luna, Roberto Montes-De- Lee-Gonzalez, Aurora Rivas-Estilla, Ana |
| Copyright Year | 2021 |
| Description | The progression and distribution of the SARS-CoV-2 pandemic are continuously changing over time and can be traced by blood donors’ serological survey. Here, we investigated the seroprevalence of anti-SARS-CoV-2 antibodies in blood donors in Nuevo Leon, Mexico during 2020 as a strategy for the rapid evaluation of the spread of SARS-CoV-2 and asymptomatic case detection. We collected residual plasma samples from blood donors who attended two regional donation centers from January to December of 2020 to identify changes in anti-SARS-CoV-2 IgG prevalence. Plasma samples were analyzed on the Abbott Architect instrument using the commercial Abbott SARS-CoV-2 IgG chemiluminescent assay. We found a total of 99 reactive samples from 2068 analyzed plasma samples, resulting in a raw prevalence of 4.87%. Donors aged 18–49 years were more likely to be seropositive compared to those aged >50 years (p < 0.001). Weekly seroprevalence increased from 1.8% during the early pandemic stage to 27.59% by the end of the year. Prevalence was 1.46-fold higher in females compared to males. Case geographical mapping showed that Monterrey city recorded the majority of SARS-CoV-2 cases. These results show that there is a growing trend of seroprevalence over time associated with asymptomatic infection that is unnoticed under the current epidemiological surveillance protocols. |
| Starting Page | 1225 |
| e-ISSN | 19994915 |
| DOI | 10.3390/v13071225 |
| Journal | Viruses |
| Issue Number | 7 |
| Volume Number | 13 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-06-24 |
| Access Restriction | Open |
| Subject Keyword | Viruses Tropical Medicine Blood Donors Covid-19 Anti-sars-cov-2 Igg Seroprevalence Mexico |
| Content Type | Text |
| Resource Type | Article |
