NDLI: Increasing Measles Seroprevalence in a Sample of Pediatric and Adolescent Population of Tuscany (Italy): A Vaccination Campaign Success

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Increasing Measles Seroprevalence in a Sample of Pediatric and Adolescent Population of Tuscany (Italy): A Vaccination Campaign Success

Content Provider	MDPI
Author	Zanella, Beatrice Boccalini, Sara Bonito, Benedetta Riccio, Marco Del Tiscione, Emilia Bonanni, Paolo Bechini, Angela
Copyright Year	2020
Description	Background: Despite the National Plan for the Elimination of Measles and congenital Rubella (NPEMcR), in 2017, a measles outbreak occurred in Italy, due to sub-optimal vaccination coverage (Methods: The enzyme-linked immunosorbent assay (ELISA) was applied for a qualitative measurement of anti-measles antibodies on 165 sera. The anamnestic and vaccination status was also collected. Results: No measles notification was reported. The overall seropositivity was 88.5%; mostly in the 5–9 years old subjects (97.9%). Among the 152 vaccinated, 92.1% were positive. The seropositivity persisted after many years since the last dose of vaccine and tended to be more long-lasting in those who had received two or three doses. The susceptibility towards measles decreased over time, reaching a lower value in the current survey (8.5%) than in 2003 (30.8%) and in 2005–2006 (25.5%). Conclusions: This study confirmed the anti-measles vaccination campaign success, which allowed for the increase in vaccination coverage and immunity levels against measles in the Florentine pediatric and adolescent population following the NPEMcR implementation.
Starting Page	512
e-ISSN	2076393X
DOI	10.3390/vaccines8030512
Journal	Vaccines
Issue Number	3
Volume Number	8
Language	English
Publisher	MDPI
Publisher Date	2020-09-08
Access Restriction	Open
Subject Keyword	Vaccines Infectious Diseases Measles Elimination Vaccination Pediatric Adolescence Seroprevalence Italy Vaccination Coverage Vaccination Effectiveness Mmrv Vaccination
Content Type	Text
Resource Type	Article

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