NDLI: Use of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) via Multiple Imaging Modalities and Modifications to Reduce Cytotoxicity: An Educational Review

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Use of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) via Multiple Imaging Modalities and Modifications to Reduce Cytotoxicity: An Educational Review

Content Provider	MDPI
Author	Nelson, Nicholas R. Port, John D. Pandey, Mukesh K.
Copyright Year	2020
Description	The aim of the present educational review on superparamagnetic iron oxide nanoparticles (SPIONs) is to inform and guide young scientists and students about the potential use and challenges associated with SPIONs. The present review discusses the basic concepts of magnetic resonance imaging (MRI), basic construct of SPIONs, cytotoxic challenges associated with SPIONs, shape and sizes of SPIONs, site-specific accumulation of SPIONs, various methodologies applied to reduce cytotoxicity including coatings with various materials, and application of SPIONs in targeted delivery of chemotherapeutics (Doxorubicin), biotherapeutics (DNA, siRNA), and positron emission tomography (PET) imaging applications.
Ending Page	135
Page Count	31
Starting Page	105
e-ISSN	2624845X
DOI	10.3390/jnt1010008
Journal	Journal of Nanotheranostics
Issue Number	1
Volume Number	1
Language	English
Publisher	MDPI
Publisher Date	2020-12-09
Access Restriction	Open
Subject Keyword	Journal of Nanotheranostics Biomedical Engineering Superparamagnetic Iron Oxide Nanoparticles (spions) Iron Oxide Nanoparticles (ionps)
Content Type	Text
Resource Type	Article

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