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The Multifaceted Effects of Gut Microbiota on the Immune System of the Intestinal Mucosa
| Content Provider | MDPI |
|---|---|
| Author | Hirano, Takehiro Nakase, Hiroshi |
| Copyright Year | 2021 |
| Description | The gut microbiota has diverse microbial components, including bacteria, viruses, and fungi. The interaction between gut microbiome components and immune responses has been studied extensively over the last decade. Several studies have reported the potential role of the gut microbiome in maintaining gut homeostasis and the development of disease. The commensal microbiome can preserve the integrity of the mucosal barrier by acting on the host immune system. Contrastingly, dysbiosis-induced inflammation can lead to the initiation and progression of several diseases through inflammatory processes and oxidative stress. In this review, we describe the multifaceted effects of the gut microbiota on several diseases from the perspective of mucosal immunological responses. |
| Ending Page | 594 |
| Page Count | 12 |
| Starting Page | 583 |
| e-ISSN | 26735601 |
| DOI | 10.3390/immuno1040041 |
| Journal | Immuno |
| Issue Number | 4 |
| Volume Number | 1 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-12-13 |
| Access Restriction | Open |
| Subject Keyword | Immuno Gut Microbiota Mucosal Immunity Metabolites Inflammatory Bowel Disease Colon Carcinogenesis Covid-19 |
| Content Type | Text |
| Resource Type | Article |