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Adverse Clinical Outcomes among Inflammatory Bowel Disease Patients Treated for Urinary Tract Infection
| Content Provider | MDPI |
|---|---|
| Author | Ukashi, Offir Barash, Yiftach Klang, Eyal Zilberman, Tal Ungar, Bella Kopylov, Uri Ben-Horin, Shomron Veisman, Ido |
| Copyright Year | 2022 |
| Description | Background: Urinary tract infection (UTI) is the most common urologic complication among patients with inflammatory bowel disease (IBD). However, data regarding UTI outcomes in this population are scarce. We aimed to evaluate adverse outcomes of UTI among patients with IBD. Methods: This was a retrospective cohort study of consecutive adult patients who visited the emergency room (ER) at Sheba Medical Center due to a UTI between 2012 and 2018. Data included demographic and clinical variables. UTI cases were extracted using ICD-10 coding. Results: Of 21,808 (ER) visits with a UTI, 122 were IBD patients (Crohn’s disease—52, ulcerative colitis—70). Contrary to non-IBD subjects, patients with IBD had higher rates of hospitalization, acute kidney injury (AKI) and 30 day-recurrent hospitalization (59.3% vs. 68.9%, p = 0.032; 4.6% vs. 13.9%, p < 0.001; 7.3% vs. 15.6%, p = 0.001, respectively). Among patients with IBD, advanced age (p = 0.005) and recent hospitalization (p = 0.037) were associated with increased risk for hospitalization, while hydronephrosis (p = 0.005), recent hospitalization (p = 0.011) and AKI (p = 0.017) were associated with increased 30-day recurrent hospitalization. Neither immunosuppressants nor biologics were associated with UTI outcomes among patients with IBD. Conclusions: Patients with IBD treated for a UTI had higher rates of hospitalization, AKI and 30-day recurrent hospitalization than non-IBD patients. No association was observed between immunosuppressants or biologics and UTI outcomes. |
| Starting Page | 1359 |
| e-ISSN | 20770383 |
| DOI | 10.3390/jcm11051359 |
| Journal | Journal of clinical medicine |
| Issue Number | 5 |
| Volume Number | 11 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-03-01 |
| Access Restriction | Open |
| Subject Keyword | Journal of clinical medicine Journal of Clinical Medicine Womens Studies Acute Kidney Injury Urinary Tract Infection 30-day-recurrent Hospitalization Crohn's Disease Ulcerative Colitis Inflammatory Bowel Disease |
| Content Type | Text |
| Resource Type | Article |
