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  1. Biosensors
  2. Volume: 4
  3. Issue: 3
  4. Biosensors with Built-In Biomolecular Logic Gates for Practical Applications
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Volume: 8
Volume: 7
Volume: 6
Volume: 5
Volume: 4
Issue: 4
Issue: 3
Microelectrode Arrays and the Use of PEG-Functionalized Diblock Copolymer Coatings
Piezoelectric Biosensors for Organophosphate and Carbamate Pesticides: A Review
Biosensors with Built-In Biomolecular Logic Gates for Practical Applications
Study of Paclitaxel-Treated HeLa Cells by Differential Electrical Impedance Flow Cytometry
Electrochemical Biosensors Based on Ferroceneboronic Acid and Its Derivatives: A Review
Sensing Magnetic Directions in Birds: Radical Pair Processes Involving Cryptochrome
An Inexpensive, Fast and Sensitive Quantitative Lateral Flow Magneto-Immunoassay for Total Prostate Specific Antigen
Magnetic Properties of FeNi-Based Thin Film Materials with Different Additives
Issue: 2
Issue: 1
Volume: 3
Volume: 2
Volume: 1

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Biosensors with Built-In Biomolecular Logic Gates for Practical Applications

Content Provider MDPI
Author Lai, Yu-Hsuan Sun, Sin-Cih Chuang, Min-Chieh
Abstract Molecular logic gates, designs constructed with biological and chemical molecules, have emerged as an alternative computing approach to silicon-based logic operations. These molecular computers are capable of receiving and integrating multiple stimuli of biochemical significance to generate a definitive output, opening a new research avenue to advanced diagnostics and therapeutics which demand handling of complex factors and precise control. In molecularly gated devices, Boolean logic computations can be activated by specific inputs and accurately processed via bio-recognition, bio-catalysis, and selective chemical reactions. In this review, we survey recent advances of the molecular logic approaches to practical applications of biosensors, including designs constructed with proteins, enzymes, nucleic acids, nanomaterials, and organic compounds, as well as the research avenues for future development of digitally operating “sense and act” schemes that logically process biochemical signals through networked circuits to implement intelligent control systems.
File Size 1328128
Ending Page 300
Page Count 28
Starting Page 273
File Format PDF
e-ISSN 20796374
DOI 10.3390/bios4030273
Journal Biosensors
Issue Number 3
Volume Number 4
Language English
Publisher Date 2014-08-27
Access Restriction Open
Subject Keyword biosensor molecular computing logic gate biomedical application
Content Type Text
Resource Type Article
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