NDLI: Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review

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Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review

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Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review

Content Provider	MDPI
Author	Chaudhari, Atul Vig, Komal Baganizi, Dieudonné Sahu, Rajnish Dixit, Saurabh Dennis, Vida Singh, Shree Pillai, Shreekumar
Abstract	Over centuries, the field of regenerative skin tissue engineering has had several advancements to facilitate faster wound healing and thereby restoration of skin. Skin tissue regeneration is mainly based on the use of suitable scaffold matrices. There are several scaffold types, such as porous, fibrous, microsphere, hydrogel, composite and acellular, etc., with discrete advantages and disadvantages. These scaffolds are either made up of highly biocompatible natural biomaterials, such as collagen, chitosan, etc., or synthetic materials, such as polycaprolactone (PCL), and poly-ethylene-glycol (PEG), etc. Composite scaffolds, which are a combination of natural or synthetic biomaterials, are highly biocompatible with improved tensile strength for effective skin tissue regeneration. Appropriate knowledge of the properties, advantages and disadvantages of various biomaterials and scaffolds will accelerate the production of suitable scaffolds for skin tissue regeneration applications. At the same time, emphasis on some of the leading challenges in the field of skin tissue engineering, such as cell interaction with scaffolds, faster cellular proliferation/differentiation, and vascularization of engineered tissues, is inevitable. In this review, we discuss various types of scaffolding approaches and biomaterials used in the field of skin tissue engineering and more importantly their future prospects in skin tissue regeneration efforts.
File Size	2667520
File Format	PDF
e-ISSN	14220067
DOI	10.3390/ijms17121974
Journal	International Journal of Molecular Sciences
Issue Number	12
Volume Number	17
Language	English
Publisher Date	2016-11-25
Access Restriction	Open
Subject Keyword	scaffolds biomaterials synthetic natural polymer skin wound healing tissue engineering
Content Type	Text
Resource Type	Article

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