NDLI: Nanoparticle-Based Systems for T1-Weighted Magnetic Resonance Imaging Contrast Agents

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Nanoparticle-Based Systems for T1-Weighted Magnetic Resonance Imaging Contrast Agents

Intra-Species Bacterial Quorum Sensing Studied at Single Cell Level in a Double Droplet Trapping System

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Nanoparticle-Based Systems for T1-Weighted Magnetic Resonance Imaging Contrast Agents

Content Provider	MDPI
Author	Zhu, Derong Liu, Fuyao Ma, Lina Liu, Dianjun Wang, Zhenxin
Abstract	Because magnetic resonance imaging (MRI) contrast agents play a vital role in diagnosing diseases, demand for new MRI contrast agents, with an enhanced sensitivity and advanced functionalities, is very high. During the past decade, various inorganic nanoparticles have been used as MRI contrast agents due to their unique properties, such as large surface area, easy surface functionalization, excellent contrasting effect, and other size-dependent properties. This review provides an overview of recent progress in the development of nanoparticle-based T1-weighted MRI contrast agents. The chemical synthesis of the nanoparticle-based contrast agents and their potential applications were discussed and summarized. In addition, the recent development in nanoparticle-based multimodal contrast agents including T1-weighted MRI/computed X-ray tomography (CT) and T1-weighted MRI/optical were also described, since nanoparticles may curtail the shortcomings of single mode contrast agents in diagnostic and clinical settings by synergistically incorporating functionality.
File Size	1602560
Ending Page	10607
Page Count	17
Starting Page	10591
File Format	PDF
e-ISSN	14220067
DOI	10.3390/ijms140510591
Journal	International Journal of Molecular Sciences
Issue Number	5
Volume Number	14
Language	English
Publisher Date	2013-05-21
Access Restriction	Open
Subject Keyword	$T_{1}-weighted$ magnetic resonance molecular imaging nanoparticles contrast agents
Content Type	Text
Resource Type	Article

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