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| Content Provider | MDPI |
|---|---|
| Author | Edziri, Hayet Mastouri, Maha Mahjoub, Mohamed Ali Mighri, Zine Mahjoub, Aouni Verschaeve, Luc |
| Abstract | We have investigated the antibacterial, antifungal and cytotoxic activities of two flavonoids isolated from Retama raetam flowers using the disc diffusion and micro-dilution broth methods. The cytotoxic activity was tested against Hep-2 cells using the MTT assay. The compounds licoflavone C (1) and derrone (2) were active against Pseudomonas aeruginosa and Escherichia coli (7.81–15.62 µg/mL) and showed important antifungal activity. Strong antifungal activity against Candida species (7.81 µg/mL) was for example found with compound 2. The tested compounds also showed strong cytotoxicity against Hep-2 cells. These two compounds may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens. |
| File Size | 204800 |
| Ending Page | 7293 |
| Page Count | 10 |
| Starting Page | 7284 |
| File Format | |
| e-ISSN | 14203049 |
| DOI | 10.3390/molecules17067284 |
| Journal | Molecules |
| Issue Number | 6 |
| Volume Number | 17 |
| Language | English |
| Publisher Date | 2012-06-13 |
| Access Restriction | Open |
| Subject Keyword | Retama raetam flowers antibacterial activity antifungal activity cytotoxic property flavonoid |
| Content Type | Text |
| Resource Type | Article |
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