NDLI: PAPIN A NOVEL MULTIPLE PSD-95/Dlg-A/ZO-1 PROTEIN INTERACTING WITH NEURAL PLAKOPHILIN-RELATED Armadillo REPEAT PROTEIN/δ-CATENIN AND p0071

Content Provider	Journal of Biological Chemistry (JBC)
Author	Deguchi, Maki Iizuka, Toshihiko Hata, Yutaka Nishimura, Wataru Hirao, Kazuyo Yao, Ikuko Kawabe, Hiroshi Takai, Yoshimi
Abstract	A neural plakophilin-relatedarmadillo repeat protein (NPRAP)/δ-catenin interacts with one of Alzheimer disease-related gene products, presenilin 1. We have previously reported the interaction of NPRAP/δ-catenin with synaptic scaffolding molecule, which is involved in the assembly of synaptic components. NPRAP/δ-catenin also interacts with E-cadherin and β-catenin and is implicated in the organization of cell-cell junctions. p0071, a ubiquitous isoform of NPRAP/δ-catenin, is localized at desmosomes in HeLa and A431 cells and at adherens junctions in Madin-Darby bovine kidney cells. We have identified here a novel protein interacting with NPRAP/δ-catenin and p0071 and named this protein plakophilin-related armadillo repeat protein-interacting PSD-95/Dlg-A/ZO-1 (PDZ) protein (PAPIN). PAPIN has six PDZ domains and binds to NPRAP/δ-catenin and p0071 via the second PDZ domain. PAPIN and p0071 are ubiquitously expressed in various tissues and are localized at cell-cell junctions in normal rat kidney cells and bronchial epithelial cells. PAPIN may be a scaffolding protein connecting components of epithelial junctions with p0071.
Related Links	http://www.jbc.org/content/275/38/29875.abstract
Ending Page	29880
Starting Page	29875
Page Count	6
File Format	HTM / HTML PDF
ISSN	00219258
Journal	Journal of Biological Chemistry (JBC)
Issue Number	38
Volume Number	275
DOI	10.1074/jbc.M005384200
e-ISSN	1083351X
Language	English
Publisher	American Society for Biochemistry and Molecular Biology
Publisher Date	2000-09-22
Access Restriction	Open
Subject Keyword	Neural plakophilin-related armadillo repeat protein (NPRAP) PSD-95/Dlg-A/ZO-1 (PDZ) Plakophilin-related armadillo repeat protein-interacting PDZ protein (PAPIN) GlutathioneS-transferase (GST) Phosphate-buffered saline (PBS) Synaptic plasma membrane (SPM) MOLECULAR BASIS OF CELL AND DEVELOPMENTAL BIOLOGY
Alternative Title	PAPIN
Content Type	Text
Resource Type	Article
Subject	Cell Biology Biochemistry Molecular Biology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Densin-180 Interacts with δ-Catenin/Neural Plakophilin-related Armadillo Repeat Protein at Synapses

δ-Catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1

Identification of a Novel PSD-95/Dlg/ZO-1 (PDZ)-like Protein Interacting with the C Terminus of Presenilin-1

The Erbin PDZ Domain Binds with High Affinity and Specificity to the Carboxyl Termini of δ-Catenin and ARVCF

BEGAIN (Brain-enriched Guanylate Kinase-associated Protein), a Novel Neuronal PSD-95/SAP90-binding Protein

Interaction of Two Actin-binding Proteins, Synaptopodin and α-Actinin-4, with the Tight Junction Protein MAGI-1

MAGUIN, a Novel Neuronal Membrane-associated Guanylate Kinase-interacting Protein

PSD-95 Assembles a Ternary Complex with theN-Methyl-d-aspartic Acid Receptor and a Bivalent Neuronal NO Synthase PDZ Domain

Cyclic Peptides as Non-carboxyl-terminal Ligands of Syntrophin PDZ Domains

PAPIN A NOVEL MULTIPLE PSD-95/Dlg-A/ZO-1 PROTEIN INTERACTING WITH NEURAL PLAKOPHILIN-RELATED Armadillo REPEAT PROTEIN/δ-CATENIN AND p0071

Similar Documents

Densin-180 Interacts with δ-Catenin/Neural Plakophilin-related Armadillo Repeat Protein at Synapses

δ-Catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1

Identification of a Novel PSD-95/Dlg/ZO-1 (PDZ)-like Protein Interacting with the C Terminus of Presenilin-1

The Erbin PDZ Domain Binds with High Affinity and Specificity to the Carboxyl Termini of δ-Catenin and ARVCF

BEGAIN (Brain-enriched Guanylate Kinase-associated Protein), a Novel Neuronal PSD-95/SAP90-binding Protein

Interaction of Two Actin-binding Proteins, Synaptopodin and α-Actinin-4, with the Tight Junction Protein MAGI-1

MAGUIN, a Novel Neuronal Membrane-associated Guanylate Kinase-interacting Protein

PSD-95 Assembles a Ternary Complex with theN-Methyl-d-aspartic Acid Receptor and a Bivalent Neuronal NO Synthase PDZ Domain

Cyclic Peptides as Non-carboxyl-terminal Ligands of Syntrophin PDZ Domains

PAPIN A NOVEL MULTIPLE PSD-95/Dlg-A/ZO-1 PROTEIN INTERACTING WITH NEURAL PLAKOPHILIN-RELATED Armadillo REPEAT PROTEIN/δ-CATENIN AND p0071