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| Content Provider | IET Digital Library |
|---|---|
| Author | Guo, Aiying Sun, Yanfeng Xu, Xiaoyue Yu, Xiumin Wu, Xiaojie Cai, Aijun Qin, Ling |
| Abstract | In this work, a facile and green approach for the synthesis of polydopamine/reduced graphene oxide nanosheets with incorporated copper ions (Cu/PDA/RGO) has been reported using bioadhesive PDA. During the process, the coating of PDA occurred through self-assembly and oxidative polymerisation, involving both the reduction of GO nanosheets and immobilisation of Cu ions. The Cu/PDA/RGO nanosheets showed effective and efficient antibacterial performance against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). The antibacterial mechanism of the Cu/PDA/RGO nanosheets was also investigated. The death of E. coli cells could be attributed to the disruption of their cell membranes and increased levels of intracellular reactive oxygen species (ROS). However, due to the direct contact between the Cu/PDA/RGO nanosheets and cells, the production of high level ROS ultimately led to the death of S. aureus cells. This research provides a new idea for the synthesis of antibacterial agents. |
| Starting Page | 114 |
| Ending Page | 118 |
| Page Count | 5 |
| Volume Number | 15 |
| e-ISSN | 17500443 |
| Issue Number | Issue 2, Feb (2020) |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/mnl/15/2 |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/10.1049/mnl.2019.0524 |
| Journal | Micro & Nano Letters |
| Publisher Date | 2020-02-05 |
| Access Restriction | Open |
| Rights Holder | © The Institution of Engineering and Technology |
| Subject Keyword | Antibacterial Activity Antibacterial Agents Antibacterial Performance Bioadhesive PDA Biomedical Material Biomembranes Cell Membranes Cellular Biophysics Coating Copper Copper Ions Cu-CO Diamond E. Coli Cell Death Escherichia Coli Facile Synthesis Filled Polymers GO Nanosheets Graphene Compound Green Approach Intercalation Compound Intracellular Reactive Oxygen Species Microorganisms Nanocomposite Nanofabrication Nanomedicine Nanotechnology Application in Biomedicine Natural And Artificial Biomembranes Oxidative Polymerisation Physics of Subcellular Structure Polydopamine-reduced Graphene Oxide Nanosheets Polymer Reactions And Polymerization Polymer-based CompoSite Polymerisation Preparation of Fullerenes And Fullerene-related Material Preparation of Reinforced Polymers Self-assembly Self-assembly in Nanofabrication Staphylococcus Aureus |
| Content Type | Text |
| Resource Type | Article |
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