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| Content Provider | IET Digital Library |
|---|---|
| Author | Yazdi, Mohammad Ehsan Taghavizadeh Darroudi, Majid Amiri, Mohammad Sadegh Hosseini, Hasan Ali Nourbakhsh, Fahimeh Mashreghi, Mohammad Farjadi, Malihe Kouhi, Seyed Mousa Mousavi Mousavi, Seyed Hadi |
| Abstract | Biosynthesis of nanoparticles (NPs) is gaining attention due to the presence of functional plant macromolecules that benefit from NPs’ synthesis and also due to their exceptional bioactive compounds. Artemisia kopetdaghensis extract acted as a reducing/capping agent. Characterisation of greener-synthesised AgNPs (Ak-AgNPs) was performed by various techniques, such as Ultraviolet (UV)−visible spectrophotometry, TEM, Fourier transform infrared, and XRD. Ak-AgNPs indicated great bactericidal properties in terms of zone of inhibition (ZI) against all of the pathogenic bacteria (i.e. Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Streptococcus pyogenes, Staphylococcus epidermidis, and Staphylococcus aureus). The maximum ZI of Ak-AgNPs was 22.3 and 17.8 mm against K. pneumoniae and S. aureus, respectively. Anti-proliferative activity of Ak-AgNPs on human hepatocellular cancer cell line (HepG2) using the MTT test showed dosage-dependent inhibition activity of Ak-AgNPs against HepG2 cancer cells. Also, green-synthesised Ak-AgNPs showed catalytic properties under UV-light in organic dye (methylene blue) degradation. This study revealed that the green-synthesised AgNPs using A. kopetdaghensis shoots extract had antibacterial and catalytic activities. Also, Ak-AgNPs had anti-proliferative potential against human liver cancer cell lines. The green-synthesised Ak-AgNPs have the potential to be exploited in anti-bacterial, anticancer, and biocatalyst technologies. |
| Starting Page | 1046 |
| Ending Page | 1050 |
| Page Count | 5 |
| Volume Number | 15 |
| e-ISSN | 17500443 |
| Issue Number | Issue 14, Dec (2020) |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/mnl/15/14 |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/10.1049/mnl.2020.0387 |
| Journal | Micro & Nano Letters |
| Publisher Date | 2020-12-16 |
| Access Restriction | Open |
| Rights Holder | © The Institution of Engineering and Technology |
| Subject Keyword | Antibacterial Activity Artemisia Kopetdaghensis Biomedical Material Biosynthesised Silver Nanoparticle Cancer Catalysis Cellular Biophysics Dye Degradation Activity Dyes Escherichia Coli Fourier Transform Infrared Spectra Green-synthesised Ak-AgNPs HepG2 Cancer Cell Human Hepatocellular Cancer Cell Line Klebsiella Pneumoniae Liver Methylene Blue Microorganisms Nanofabrication Nanomedicine Nanoparticle Nanotechnology Application in Biomedicine Pseudomonas Aeruginosa Silver Compound Spectrophotometry Staphylococcus Aureus Staphylococcus Epidermidis Streptococcus Pyogenes Toxicology Transmission Electron Microscopy Ultraviolet Spectra Ultraviolet-visible Spectrophotometry Visible Spectra X-Ray Diffraction XRD |
| Content Type | Text |
| Resource Type | Article |
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