NDLI: Investigative evaluation of Cassia absus for antibacterial capacity and biomimetic synthesis of silver nanoparticles

Content Provider	IET Digital Library
Author	Jehan, Mehreen Saeed, Fiza Khan, Zanib Shah, Muddassar Sikandar, Ayesha Inayat, Afia Ali, Sartaj Khan, Arshad Mehmood Talib, Ayesha Aasim, Muhammad Khan, Abid Ali
Abstract	Cassia absus is used for medicinal purposes for a long time all over the world. In this study, the authors report the antimicrobial potential of C. absus extracts obtained with different solvents. The extract(s) obtained with ethyl acetate yielded the best antibacterial effects because of a rich supply of oxalates and alkaloids in it. The same extract was also exploited for reducing Ag+ ions (to metallic Ag0) for the synthesis of nanoparticles. Electron microscopy revealed that the silver nanoparticles were ∼18–25 nm in diameter. The Fourier-transform infrared evaluation pointed towards the fact that flavonoids present in the plant extract were acting as reductants while amino groups were the bound stabilisation agents to the synthesised nanoparticles limiting the diameter to a certain threshold and avoiding aggregation naturally. A comparative antibacterial assay of C. absus versus Ag nanoparticles showed that the nanoparticles as well as organic (ethyl acetate) extract of the plant checked the growth of selected (MDR) superbugs. However, the biosynthesised Ag nanoparticles returned better antibacterial efficacies than ethyl acetate extract.
Starting Page	1062
Ending Page	1066
Page Count	5
ISSN	17518741
Volume Number	12
e-ISSN	1751875X
Issue Number	Issue 8, Dec (2018)
Alternate Webpage(s)	https://digital-library.theiet.org/content/journals/iet-nbt/12/8
Alternate Webpage(s)	https://digital-library.theiet.org/content/journals/10.1049/iet-nbt.2018.5054
Journal	IET Nanobiotechnology
Publisher Date	2018-07-27
Access Restriction	Open
Rights Holder	© The Institution of Engineering and Technology
Subject Keyword	Alkaloids Antibacterial Activity Antibacterial Assay Antibacterial Capacity Antibacterial Efficacies Antimicrobial Potential Biomedical Material Biomimetic Synthesis Biomimetics Cassia Absus Electron Microscopy Ethyl Acetate Flavonoids Fourier Transform Infrared Spectra Fourier-transform Infrared Evaluation Microorganisms Nanofabrication Nanomedicine Nanoparticle Nanotechnology Application in Biomedicine Nanotube And Nanostructured Material Organic Extract Oxalates Reduction (Chemical) Silver Compound Silver NanoParticle Structure of Solid Clusters
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering Biotechnology

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