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| Content Provider | IET Digital Library |
|---|---|
| Author | Zhang, Yajun Gao, Kexin Fan, Yiqiang |
| Abstract | This study proposed a rapid and reliable approach for the bonding of thermoplastic-based microfluidics with a new, low-cost, low toxic, and transparent ultraviolet (UV) curable adhesive as the intermediate layer between thermoplastic plates. After laser fabrication of microchannels on the surface of the polymethyl methacrylate (PMMA) substrate, the UV curable adhesive layer is applied between the substrate and cover plate; a flushing process is then conducted for the removal of the adhesive residuals inside the microchannel. Finally, a UV exposure with the wavelength of 365 nm is applied for the crosslinking of adhesives to finish the bonding process. Several microfluidic devices were fabricated and tested for the demonstration of the proposed technique, and the bonding strength was carefully measured with different UV exposure duration. The characteristics of the contact angle and UV–visible spectroscopy of the UV adhesive coated surface are also provided in this study. In addition, a simple biocompatibility test of the UV curable adhesive-coated polymer surface is also conducted in this research to confirm the low toxicity of the adhesive layer. The proposed bonding techniques are broadly applicable to achieve a rapid, low-cost, optically clear, and low toxic bonding for thermoplastic-based microfluidics. |
| Starting Page | 211 |
| Ending Page | 214 |
| Page Count | 4 |
| Volume Number | 14 |
| e-ISSN | 17500443 |
| Issue Number | Issue 2, Feb (2019) |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/mnl/14/2 |
| Alternate Webpage(s) | https://digital-library.theiet.org/content/journals/10.1049/mnl.2018.5479 |
| Journal | Micro & Nano Letters |
| Publisher Date | 2019-02-06 |
| Access Restriction | Open |
| Rights Holder | © The Institution of Engineering and Technology |
| Subject Keyword | Adhesive Residuals Adhesives Applied Fluid Mechanics Biocompatibility Test Biomedical Engineering Biomedical Measurement And Imaging BioMEMS Biophysical Instrumentation And Technique Bonding Process Bonding Processes Bonding Strength Bonding Technique Condensed Matter Contact Angle Cover Plate Fabrication of MEMS And NEMS Device Flushing Process Laser Fabrication Laser Material Processing Low Toxic Bonding Low Toxicity Microchannels Microfabrication Microfluidic Device Microfluidics Micromechanical And Nanomechanical Device And System Other Topics in Material Science Plate PMMA Substrate Polymer Rapid Bonding Thermoplastic Plate Thermoplastic-based Microfluidics Ultraviolet Spectra UV Adhesive Coated Surface UV Curable Adhesive Layer UV Curable Adhesive-coated Polymer Surface UV Exposure Duration UV-visible Spectroscopy Visible And Ultraviolet Spectra Visible Spectra |
| Content Type | Text |
| Resource Type | Article |
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