NDLI: Force-controlled ultrasound robot for consistent tissue pre-loading: Implications for acoustic radiation force elasticity imaging

Content Provider	IEEE Xplore Digital Library
Author	Lediju Bell, M.A. Sen, H.T. Iordachita, I. Kazanzides, P.
Copyright Year	2014
Description	Author affiliation: Dept. of Comput. Sci., Johns Hopkins Univ., Baltimore, MD, USA (Lediju Bell, M.A.; Sen, H.T.; Kazanzides, P.) \|\| Dept. of Mech. Eng., Johns Hopkins Univ., Baltimore, MD, USA (Iordachita, I.)
Abstract	Acoustic radiation force (ARF)-based measurements of tissue elasticity require transmission of an acoustic pulse and ultrasound image-based tracking of the resulting tissue displacements. This technique provides diagnostic information about various disease states of tissue. One limitation, however, is the dependency on applied probe pressure, which is difficult to control manually and prohibits standardization of quantitative measurements. To overcome this limitation, we introduce a custom-built robot that controls probe contact forces. The robot was evaluated in an in vivo canine prostate and ex vivo bovine liver. Markers implanted in the prostate were visualized with 3D probe contact forces (i.e. tissue pre-loading) that ranged 10-11 N. The resulting displacement of the markers were evaluated to estimate the variability in pre-loading strains that could exist prior to making an ARF-based elasticity measurement. One standard deviation of corresponding strains ranged 0-2%. In the ex vivo liver, differences in speckle-tracked tissue displacements were observed when the probe sustained tissue contact as it returned to its initial position, indicating that there is a potential benefit in losing tissue contact prior to taking measurements that will be used for standardization (e.g. to avoid differences in pre-loading and corresponding tissue elasticity). Results are promising for the introduction of robotic systems to control the applied probe pressure for ARF-based measurements of tissue elasticity.
Starting Page	259
Ending Page	264
File Size	1911636
Page Count	6
File Format	PDF
ISBN	9781479931262
ISSN	21551774
e-ISBN	9781479931286
DOI	10.1109/BIOROB.2014.6913786
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2014-08-12
Publisher Place	Brazil
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Ultrasonic imaging Force measurement Force Elasticity Probes Robots Strain
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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