NDLI: A Simplified Production Method for Multimode Multisite Neuroprobes

Content Provider	IEEE Xplore Digital Library
Author	Mankodiya, K. Krapohl, D. Hammad, S. Xie, Y. Klinger, M. Hofmann, U.G.
Copyright Year	2009
Description	Author affiliation: Institute for Anatomy, University of Luebeck, Germany (Klinger, M.) \|\| Institute for Signal Processing, University of Luebeck, Germany (Mankodiya, K.; Krapohl, D.; Hammad, S.; Hofmann, U.G.) \|\| Graduate School for Computing in Medicine and Life Sciences, University of Luebeck, Germany (Xie, Y.)
Abstract	Unified electro-optical microprobes for co-localized optical and electrical recordings within a rats brain have been recently introduced (Krapohl, Bonin et al. 2008). In this work, we show a simplified production method for these multimodal multisite neuroprobes. The electro-optical neuroprobe has an outer diameter of 255µm and is composed of eight NiChrome wires (Ø 25µm) fixed to the surface of a mono-mode glass fiber (Ø 125µm). Where the former method elaborately braids the wires around the fiber, the new method uses the property of a PTFE tube to shrink at higher temperature (≫300°C). Thus the microwires are pressed to the fiber. The probe tip is than hand polished and is such ready to be used in rat brain navigation experiments, featuring both functions electrical as well as anatomical, optical look-ahead properties. The latter is achieved by using the glassfiber as working probe for an Optical Coherence Tomography (OCT) system. Hence these electrooptical probes are called OCTrodes. We determined the impedance of the OCTrodes by impedance spectroscopy to lie in the range of 500kΩ at 1kHz frequency. This range enables them to record both single and multi unit activity. OCT experiments have shown promising results in detecting transversal boundaries between structures of different density in phantoms and cadaver brain. Ongoing experiments aim at co-localized optical and electrical recordings in living animals.
Starting Page	211
Ending Page	214
File Size	1195700
Page Count	4
File Format	PDF
ISBN	9781424420728
DOI	10.1109/NER.2009.5109271
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-04-29
Publisher Place	Turkey
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	OCT Temperature Navigation Glass Rats OCTrode Niotrode Optical recording Wires Production multimodal neuroprobe Tomography Neural recording Impedance Probes
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in