NDLI: An Artificial Immune System for Temporal Anomaly Detection Using Cell Activation Thresholds and Clonal Size Regulation with Homeostasis

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2009 International Joint Conference on Bioinformatics, Systems Biology and Intelligent Computing

Table of Contents

Message from General Chair

Message from Program Chairs

Steering Committee

Program Committee

Planery Keynote Abstracts

Gene Selection for Microarray Expression Data with Imbalanced Sample Distributions

Redundant Gene Selection Based on Particle Swarm Optimization

Investigating Gene and MicroRNA Expression in Glioblastoma

Discovery of Biomarker Genes from Earthworm Microarray Data by Discriminant Analysis and Clustering

PBC: A Software Framework Facilitating Pattern-Based Clustering for Microarray Data Analysis

Cross-Domain Neurobiology Data Integration and Exploration

Study DNA Microarray Gene Expression Data of Alzheimer's Disease by Independent Component Analysis

Probabilistic Model Based Hough Transform for Detection of Co-expression Patterns in Three-Color cDNA Microarray Data

Multiclass Gene Selection on Microarray Data Using l1-norm Least Square Regression

Framework for Knowledge-Based Integrative Analysis of Microarray Data

Genome Evolution in Malaria Parasites: I. Core Genome Components

Accelerating Genome-Wide Association Studies Using CUDA Compatible Graphics Processing Units

Genomic Comparison of Bacterial Species Based on Metabolic Characteristics

The Core and Pan-Genome of the Vibrionaceae

An Improved Algorithm for the Location of Heaviest Segments in Genomic Sequences

GeneIndex: An Open Source Parallel Program for Enumerating and Locating Words in a Genome

Proteogenomic Mapping for Structural Annotation of Prokaryote Genomes

A Classification System for Predicting RNA Hairpin Loops

Layout and Post-Processing of Transcriptional Modules

Mapping miRNA Regulation to Functional Gene Sets

A Primer Design Algorithm for Global Analysis of CpG Methylation

Accurate Prediction of Alternatively Spliced Cassette Exons Using Evolutionary Conservation Information and Logitlinear Model

A Neural Network Based on Rough Set (RSNN) for Prediction of Solitary Pulmonary Nodules

Variation in the Predicted Biosynthetic Capabilities of Seven Vibrionaceae

Molecular Cloning and Expression of Ppdc-ldhL Fusion Gene in Zymomonas Mobilis ATCC 10988

Clustering of SNPs by a Structural EM Algorithm

A Parallel Algorithm for Three-Profile Alignment Method

Mapping Transcription Factors from a Model to a Non-model Organism

On the Design of RNA Sequences for Realizing Extended Shapes

Practical and Efficient Algorithms for Degenerate and Weighted Sequences Derived from High Throughput Sequencing Technologies

An Adaptive Suffix Tree Based Algorithm for Repeats Recognition in a DNA Sequence

A Bayesian Approach for Identifying miRNA Targets by Combining Sequence Prediction and Expression Profiling

Next Generation Sequence Analysis Using Genetic Algorithms on Multi-core Technology

Structural Domain Based Multiple Instance Learning for Predicting Gram-Positive Bacterial Protein Subcellular Localization

Biological Features for Sequence-Based Prediction of Protein Stability Changes upon Amino Acid Substitutions

GO Semantic Similarity Based Analysis for Huaman Protein Interactions

GO Semantic Similarity-Based False Positive Reduction of Protein-Protein Interactions

Using Mutual Information and Models of Evolution for Improved Pattern Petection

Network Approaches for Shotgun Proteomics Data Analysis

SVM-Based Approach for Predicting DNA-Binding Residues in Proteins from Amino Acid Sequences

Putative Cell Cycle Related Genes in Plasmodium Falciparum

Identifying New Methylated Arginines via Granular Decision Fusion with SVM Modeling

A Comparative Study of Ensemble Learning Approaches in the Classification of Breast Cancer Metastasis

New Descriptors of Evolutionary Information for Accurate Prediction of DNA and RNA-Binding Residues in Protein Sequences

Improving Prediction of the Contact Numbers of Residues in Proteins from Primary Sequences

Protein Remote Homology Detection Using Order Profiles

Semi-supervised Learning of Text Classification on Bacterial Protein-Protein Interaction Documents

ANN Based Protein Function Prediction Using Integrated Protein-Protein Interaction Data

3D-interologs: A Protein-Protein Interacting Evolution Database across Multiple Species

Assessing the Most Effective Depth for PPI Analysis

Discovery of Motif Pairs from Protein-Protein Interaction Networks

A Systems Biology Approach to Identify Affected Regulatory and Signaling Circuits in Protein Interaction Networks

Automaton Models of Computational Genetic Regulatory Networks with Combinatorial Gene-Protein Logical Interactions

Towards a Comprehensive HBV-Human Interaction Map

Prediction of Peptides Binding to MHC Class I Alleles by Partial Periodic Pattern Mining

MRI Based Fat Segmentation at 7T with Confidence Image

An Artificial Immune System for Temporal Anomaly Detection Using Cell Activation Thresholds and Clonal Size Regulation with Homeostasis

Global Stochastic Contact Modeling of Infectious Diseases

Optimal Overlay of Ligands with Flexible Bonds Using Differential Evolution

Analyzing Response Feasibility for Bioemergencies

Estimation of Heart Rate Variability Changes during Different Visual Stimulations Using Non-invasive Continuous ECG Monitoring System

A Study on Prognosis of Brain Tumors Using Fuzzy Logic and Genetic Algorithm Based Techniques

Feature Extraction and Classification of EEG Signals Using Wavelet Transform, SVM and Artificial Neural Networks for Brain Computer Interfaces

A Novel Method of De-noising and Classifying on Mental EEG of Imaging Left-Right Hands Movement

A Computational Framework to Study Public Health Epidemiology

Exploring Systems Biology Approaches to Traditional Chinese Medicine Cancer Research

Genomic Imaging: A Modern Environment for TCM Research

YinYang Bipolar Relativity - A Unifying Theory of Nature, Agents and Life Science

Concordance of Diagnosis Based on Zangfu-Organs Syndrome Differentiation by Clinicians of Traditional Chinese Medicine

A TCM Platform for Maters' Experience Sharing

Facial Complexion Acquisition and Recognition System for Clinical Diagnosis in Traditional Chinese Medicine

TCM in Innate Immunity: A YinYang-N-Element Hypothesis of the Innate Immunological System

In-Silico Effects of Mg2+ Diffusion Rates on Stochastic Event Based Simulation of the PhoPQ System

Global Network Features of Cancer Genes in the Human Interactome

A Granular Hierarchical Approach to Biophysical and Biochemical Evaluations of Transgenic Modifications

Integrative Computational Identifications of the Signaling Pathway Network Related to TNF-alpha Stimulus in Vascular Endothelial Cells

Using Frequent Co-expression Network to Identify Gene Clusters for Breast Cancer Prognosis

A Numerical Study of Pulsatile Flow Through a Hollow Fiber Cartridge: Growth Factor-Receptor Binding and Dissociation Analysis

Pathway and Network Analysis of Schizophrenia Candidate Genes under Meta-Analysis Linkage Peaks

Enhancing Automatic Biological Pathway Generation with GO-Based Gene Similarity

Estimation of Kinetic Rates of MAP Kinase Activation from Experimental Data

Connecting Biological Themes Using a Single Human Network of Gene Associations

Statistical Analysis of Discrete Dynamical System Models for Biological Networks

Parameterized Complexity of Finding Elementary Modes in Metabolic Networks

Two Dimensional Modeling and Fractal Characterization of Tumor Vascular Network

Gene Regulatory Network Inference Using Predictive Minimum Description Length Principle and Conditional Mutual Information

Dynamic Propagation Properties of Virus-Host Protein Interaction Network

Notice of Violation of IEEE Publication PrinciplesSystematically Identifying Genes and Pathways in Multiple Cancer Types Using HGD & PSO-SVM

Constraint Projections for Discriminative Support Vector Machines

Regularized Recurrent Least Squares Support Vector Machines

Similarity Learning via Optimizing the Data-Dependent Kernel

EasyEnsemble and Feature Selection for Imbalance Data Sets

Genetic Algorithm Based Semi-feature Selection Method

Combination Forecasting Model for Mid-long Term Load Based on Least Squares Support Vector Machines and a Mended Particle Swarm Optimization Algorithm

An Improved EM-Based Semi-supervised Learning Method

A Novel Nonlinear Dimensionality Reduction Method for Robust Wood Image Recognition

Designing the Self-Adaptive Fuzzy Neural Networks

An Effective Multi-level Immune Algorithm for Graph Bipartitionin

A Combination Approach to Cluster Validation Based on Statistical Quantiles

Collision Description of Clustering

A Vector Operation Based Fast Association Rules Mining Algorithm

A Quadratic Time Algorithm for Computing the Quartet Distance between Two General Trees

Kalman Filtering Design Based on Real-Time Updating of Noise Matrix

Applying Particle Swarm Optimization to Transfer Function Specification for Direct Volume Rendering

PTS-RNSA: A Novel Detector Generation Algorithm for Real-Valued Negative Selection Algorithm

Semantic Role Labeling Based on Dependency Tree with Multi-features

A Collaborative Car Auto-Navigation Framework Based on Intelligent Trajectory Mining

Security Data Mining in an Ontology for Vulnerability Management

Fingerprint Ridge Distance Estimation Based on Ridge Search

An Improved Asymmetric Link Bandwidth Measurement Algorithm

The Application of Improved Immunogenetic Algorithm in Signal Timing

Modeling Confidentiality in a Simplified Database Access

RFID Dynamic Grouping Anti-collision Algorithm Based on FCM

Design of Obstacle Modal Discrimination System Based on the Neural Network

Feature Mining and Intelligent Computing for MP3 Steganalysis

An Artificial Immune System for Temporal Anomaly Detection Using Cell Activation Thresholds and Clonal Size Regulation with Homeostasis

Content Provider	IEEE Xplore Digital Library
Author	Antunes, M.J. Correia, M.E.
Copyright Year	2009
Abstract	This paper presents an Artificial Immune System (AIS) based on Grossman's Tunable Activation Threshold (TAT) for anomaly detection. We describe the immunological metaphor and the algorithm adopted for T-cells, emphasizing two important features: the temporal dynamic adjustment of T-cells clonal size and its associated homeostasis mechanism. We present some promising results obtained with artificially generated data sets, aiming to test the appropriateness of using TAT in dynamic changing environments, to distinguish new unseen patterns as part of what should be detected as normal or as anomalous.
Starting Page	323
Ending Page	326
File Size	880095
Page Count	4
File Format	PDF
ISBN	9780769537399
DOI	10.1109/IJCBS.2009.59
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-08-03
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Pathogens Peptides Artificial Immune System anomaly detection Home computing homeostasis tunable activation threshold Artificial immune systems Systems biology Biology computing clonal size control Bioinformatics Intelligent systems Artificial intelligence Immune system
Content Type	Text
Resource Type	Article

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