NDLI: Shape analysis of brain structures using physical and experimental modes

Content Provider	IEEE Xplore Digital Library
Author	Martin, J. Pentland, A. Kikinis, R.
Copyright Year	1994
Description	Author affiliation: Surgical Planning Lab., Brigham & Women's Hospital, Boston, MA, USA (Martin, J.; Pentland, A.; Kikinis, R.)
Abstract	We present a framework for analyzing the shape of structures within the human brain. A mathematical model is developed describing the deformation of any brain structure whose shape is affected by both gross and detailed physical processes. The total shape deformation is decomposed into physical modes of variation obtained from finite element analysis, and experimental modes of variation obtained from sample data using principal component analysis. This mathematical model is used to classify diseases that affect the shape of the ventricular system of the brain. Because ventricular shape is affected not only by pathology but also by overall brain shape, disease discrimination is difficult. By modeling the brain's elastic properties, we are able to compensate for some of the nonpathological modes of ventricular shape variation. This allows us to experimentally characterize modes of variation that are indicative of disease processes.<>
Starting Page	752
Ending Page	755
File Size	441940
Page Count	4
File Format	PDF
ISBN	0818658258
ISSN	10636919
DOI	10.1109/CVPR.1994.323892
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1994-06-21
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Brain Image analysis Finite-element methods Biomedical computing
Content Type	Text
Resource Type	Article
Subject	Computer Vision and Pattern Recognition Software

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