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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Demongeot, J. Cohen, O. Doncescu, A. Henrion-Caude, A. |
| Copyright Year | 2013 |
| Description | Author affiliation: Dept. de Ing. Biomed., Univ. de Valparaiso, Valparaiso, Chile (Doncescu, A.) || Fac. of Med., Univ. J. Fourier Grenoble, La Tronche, France (Demongeot, J.; Cohen, O.) |
| Abstract | MicroRNAs are parts of nuclear and mitochondrial genomes which pertain to the not coding genome. They have a partly unspecific role of inhibition, preventing the weakest part of the genetic regulatory networks to be expressed and preventing the appearance of a too large number of attractors in these networks, i.e., forcing the network to have only one or two possible dynamic behaviours for fulfilling a precise function. They have also a great influence on the chromatin clock, which ensures the real mode of updating of genetic regulatory networks. We analyze this influence as well as their impact on important functions like p53 network control. |
| Starting Page | 1501 |
| Ending Page | 1508 |
| File Size | 2828061 |
| Page Count | 8 |
| File Format | |
| ISBN | 9781467362399 |
| e-ISBN | 9780769549521 |
| DOI | 10.1109/WAINA.2013.89 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2013-03-25 |
| Publisher Place | Spain |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Proteins Chromatin clock control Genetic networks RNA Genomics MicroRNAs Encoding Polymers Energetic regulation Clocks |
| Content Type | Text |
| Resource Type | Article |
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