NDLI: Diagnostics of biomedical agents by whispering gallery mode optical resonance based sensor

Content Provider	IEEE Xplore Digital Library
Author	Saetchnikov, V.A. Tcherniavskaia, E.A. Saetchnikov, A.V. Schweiger, G. Ostendorf, A.
Copyright Year	2013
Description	Author affiliation: Belarusian State Univ., Minsk, Belarus (Saetchnikov, V.A.; Tcherniavskaia, E.A.; Saetchnikov, A.V.) \|\| Ruhr-Univ., Bochum, Germany (Schweiger, G.; Ostendorf, A.)
Abstract	Experimental data on optical resonance spectra of whispering gallery modes of dielectric microspheres in antibiotic solutions under varied in wide range concentration are represented. Optical resonance was demonstrated could be detected at a laser power of less than 1 microwatt. Several antibiotics of different generations: Amoxicillin, Azithromycin, Cephazolin, Chloramphenicol, Levofloxacin, Lincomicin Benzylpenicillin, Riphampicon both in de-ionized water and physiological solution had been used for measurements. Both spectral shift and the structure of resonance spectra were of specific interest in this investigation. Drag identification has been performed by developed multilayer perceptron network. The network topology was designed included: a number of the hidden layers of multilayered perceptron, a number of neurons in each of layers, a method of training of a neural network, activation functions of layers, type and size of a deviation of the received values from required values. For a network training the method of the back propagation error in various modifications has been used. Input vectors correspond to 6 classes of biological substances under investigation. The result of classification was considered as positive when each of the region, representing a certain substance in a space: relative spectral shift of an optical resonance maxima - relative efficiency of excitation of WGM, was singly connected.
Starting Page	412
Ending Page	414
File Size	3140335
Page Count	3
File Format	PDF
ISSN	21601534
e-ISBN	9781479900183
DOI	10.1109/CAOL.2013.6657657
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-09-09
Publisher Place	Ukraine
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Training Biomedical optical imaging Optical resonators Whispering gallery modes Biology Optical sensors Optical surface waves
Content Type	Text
Resource Type	Article

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