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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Borri, P. Lutti, J. Langbein, W. |
| Copyright Year | 2009 |
| Description | Author affiliation: Cardiff University School of Physics and Astronomy, The Parade CF24 3AA, UK (Langbein, W.) || Cardiff University School of Biosciences, Museum Avenue CF10 3AX, UK (Borri, P.; Lutti, J.) |
| Abstract | A dielectric microsphere in a lower refractive index medium exhibits sharp optical resonances, called whispering gallery modes. These are sensitive probes of refractive index changes near the sphere surface and can be thus exploited for biosensing applications. Using evanescent field coupling via frustrated total internal reflection, we measured whispering gallery optical resonances of polystyrene microspheres of 30–45µm diameter, held in aqueous buffer by optical tweezers, and found Q-factors of up to $4×10^{6}.$ We also demonstrated a monolithic sensor based on polystyrene microspheres in water attached onto an optical coupler via a solid separation layer index matched to water. As a proof of principle of the sensing capabilities, we measured the response to refractive index changes and inferred a shot-noise limited precision of $1×10^{−8}$ refractive index units. |
| Starting Page | 1 |
| Ending Page | 3 |
| File Size | 214554 |
| Page Count | 3 |
| File Format | |
| ISBN | 9781424448258 |
| e-ISBN | 9781424448272 |
| DOI | 10.1109/ICTON.2009.5185193 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-06-28 |
| Publisher Place | Portugal |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Whispering gallery modes Dielectrics Biosensors Optical buffering Optical sensors Refractive index Biomedical optical imaging Optical refraction Optical surface waves Optical variables control biosensors whispering gallery modes |
| Content Type | Text |
| Resource Type | Article |
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