NDLI: A configurable architecture for the detection of DNA sequences based on a $E^{2}PROM$ device

Content Provider	IEEE Xplore Digital Library
Author	Abbati, L. Placidi, P. Scorzoni, A. Lanzoni, M.
Copyright Year	2007
Description	Author affiliation: DIEI, Perugia (Abbati, L.; Placidi, P.; Scorzoni, A.)
Abstract	The authors present a novel approach to perform the readout of a genetic sensor using a configurable architecture with extremely low drift with temperature and low sensitivity to the drift of mobile gate oxide charges. The proposed architecture, able to detect small changes of U.V. absorbance, calculates the analog weighted difference between the gate / source voltages of a floating gate and a reference nMOS transistor fabricated using a single poly technology. The theoretical dependence of the obtained results on both device and circuit parameters has carefully been analyzed. Experimental results show that the circuit offers a valid solution to decrease the error due to temperature variation during operation. Moreover, the measurement procedure is sufficiently quick for neglecting threshold voltage shifts due to mobile charges. Finally, the proposed approach has a particular advantage in integrated system design, since it is compatible with high-density MOS logic.
Starting Page	1
Ending Page	6
File Size	1241912
Page Count	6
File Format	PDF
ISBN	9781424412440
DOI	10.1109/IWASI.2007.4420011
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-06-26
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Temperature sensors Sequences Costs Nonvolatile memory DNA CMOS technology Genetics Silicon Biosensors Sensor arrays
Content Type	Text
Resource Type	Article

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