NDLI: Protein supporting structure discovery by rigid structure identification via one-dimensional structural signature

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2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops

2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)

2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)

2009 IEEE International Conference on Bioinformatics and Biomedicine Workshop

2008 IEEE International Conference on Bioinformatics and Biomeidcine Workshops

Table of contents

Proceedings 2008 IEEE international conference on bioinformatics and biomedicine workshops [Front matter]

Comparing classification methods for predicting survival probabilities in the elderly

A statistical model to correct systematic bias introduced by algorithmic thresholds in protein structural comparison algorithms

High-performance computing for drug design

Protein supporting structure discovery by rigid structure identification via one-dimensional structural signature

Comparative analysis of degradomes in unicellular malaria parasite and free-living ciliates

Analyzing dynamical simulations of intrinsically disordered proteins using spectral clustering

Inferring algebraic gene networks using local decoding

Integrated software environment for protein structure refinement

Metabolic pathway complements of eight Escherichia coli strains

An integrated database for complex protein structure modeling

Extracting biological meaning from global proteomic data on circulating-blood platelets: Effects of diabetes and storage time

Automated bone segmentation from Pelvic CT images

A new sensitivity measure for probabilistic Boolean networks based on steady-state distributions

Automated segmentation of lateral ventricles in brain CT images

An iterative approach to probe-design for compressive sensing microarrays

Automated segmentation of pelvic bone structure in x-ray radiographs using active shape models and directed Hough transform

A multimodality ICA study - integrating genomic single nucleotide polymorphisms with functional neuroimaging data

A modified maximum correlation modeling method for fMRI brain mapping; application for detecting dyslexia

Finding structured gene signatures

An intelligent listening framework for capturing encounter notes from a doctor-patient dialog

A Particle Swarm Optimization algorithm for finding DNA sequence motifs

AdaBoost-based multiple SVM-RFE for classification of mammograms in DDSM

Cancer classification by sparse representation using microarray gene expression data

Comparison of classification methods on protein-protein interaction document classification

An integrated approach of sequence and text mining technology for the identification of transcription factor binding sites

Effect of commuting on the detection and characterization performance of the Bayesian Aerosol Release Detector

Using a literature-based NMF model for discovering gene functional relationships

BioDEAL: Biological data-evidence-annotation linkage system

Protein function prediction using decision trees

A text-mining approach for classification of genomic fragments

Protein-protein recognition prediction using support vector machine based on feature vectors

A model-driven approach to manage evolving clinical and translational data in relational databases

Graph-constrained discriminant analysis of functional genomics data

Semantic analysis and classification of medical questions for a logic-based medical question-answering system

In silico prediction of target SNPs affecting miR-mRNA interaction

Clinical dementia rating score prediction based on MR segmentation

Classification of gene expression levels using activator and repressor motifs

Consistently predicting protein function based on MKL

Fuzzy rule-based Interactive gyrus labeling for the infantile brain in magnetic resonance images

Author index

2007 IEEE International Conference on Bioinformatics and Biomedicine Workshops

Protein supporting structure discovery by rigid structure identification via one-dimensional structural signature

Content Provider	IEEE Xplore Digital Library
Author	Yu-Feng Huang Chia-Jui Yang Yi-Wei Yang Chun-Chin Huang Chien-Kang Huang
Copyright Year	2008
Description	Author affiliation: Dept. of Comput. Sci. & Inf. Eng., Nat. Taiwan Univ., Taipei (Yu-Feng Huang) \|\| Dept. of Eng. Sci. & Ocean Eng., Nat. Taiwan Univ., Taipei (Chia-Jui Yang; Yi-Wei Yang; Chun-Chin Huang; Chien-Kang Huang)
Abstract	Protein function is highly correlated with its three-dimensional conformation in order to interact with others proteins, ligands, substrates, inhibitors, etc. Studies on binding site and protein function have been investigated to understand the mechanism of protein activity. The role of binding site can be characterized by the presence of stable regions and flexible regions. Furthermore, protein stability and flexibility play different roles on protein functions. In this work, we propose the framework to discover protein supporting structure by identifying rigid regions among different structure of same/similar proteins. By encoding spatial information of protein structure into structural signature, we can reduce comparison time without losing accuracy, in comparison with the time complexity of structure comparison using geometric hashing approach. Our results reveal that supporting structure can be discovered in selected enzyme families. Moreover, supporting structure plays different roles depend on the mechanism of protein activity of protein family.
Starting Page	9
Ending Page	16
File Size	706183
Page Count	8
File Format	PDF
ISBN	9781424428908
DOI	10.1109/BIBMW.2008.4686203
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2008-11-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Computer science Protein engineering Sequences Stability Inhibitors Oceans Biochemistry Encoding Libraries Nuclear magnetic resonance
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Spatial Encoding Scheme for Protein Supporting Structure Discovery

Mapping discontinuous antibody epitopes to reveal protein structure and changes in structure related to function

Structural characterization of a crude oil by one and two dimensional nuclear magnetic resonance spectroscopy

Parallel Protein Structure Prediction by Multiobjective Optimization

Structure-based tailoring of compound libraries for high-throughput screening: discovery of novel EphB4 kinase inhibitors.

Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein.

Identification of ALK5 inhibitor via structure-based virtual screening and ADMET prediction.

The difference between protein structures obtained by x-ray analysis and nuclear magnetic resonance

Captides: rigid junctions between beta sheets and small molecules.

Protein supporting structure discovery by rigid structure identification via one-dimensional structural signature

Similar Documents

Spatial Encoding Scheme for Protein Supporting Structure Discovery

Mapping discontinuous antibody epitopes to reveal protein structure and changes in structure related to function

Structural characterization of a crude oil by one and two dimensional nuclear magnetic resonance spectroscopy

Parallel Protein Structure Prediction by Multiobjective Optimization

Structure-based tailoring of compound libraries for high-throughput screening: discovery of novel EphB4 kinase inhibitors.

Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein.

Identification of ALK5 inhibitor via structure-based virtual screening and ADMET prediction.

The difference between protein structures obtained by x-ray analysis and nuclear magnetic resonance

Captides: rigid junctions between beta sheets and small molecules.

Protein supporting structure discovery by rigid structure identification via one-dimensional structural signature