NDLI: Impedometric Analysis and Characterization in the Development of an hCGß Biosensor

Content Provider	IEEE Xplore Digital Library
Author	Kassanos, P. lles, R.K. Bayford, R.H. Demosthenous, A.
Copyright Year	2007
Description	Author affiliation: Univ. Coll. London, London (Kassanos, P.)
Abstract	Detection and concentration monitoring of Human Chorionic Gonadotropin (hCG) and especially, its free beta-subunit, (hCG), is critical for various aspects of the human health. More importantly, they can be used as markers of gestational trophoblastic disease (GTD), germ cell tumors and some non-trophoblastic tumors. Detection of hCGbeta is also critical for patient treatment monitoring and for relapse detection. According to the literature, the use of hCGbeta as a tumor marker is limited by the lack of high sensitivity and specificity sensors. In this paper we present the first two steps of the development of an impedance biosensor, based on the formation of a stable antibody-antigen complex on gold microband electrodes and the preliminary results and analysis of the interface processes, relating the physical structure of the sensor to its electrical behavior using EIS. Electrical equivalent circuit models based on the experimental results are also presented.
Starting Page	94
Ending Page	97
File Size	4650841
Page Count	4
File Format	PDF
ISBN	9781424413454
DOI	10.1109/ISSMDBS.2007.4338301
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-08-19
Publisher Place	UK
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Impedance Biosensors Neoplasms Patient monitoring Humans Diseases Pathogens Medical treatment Sensitivity and specificity Gold
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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