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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Malpani, R. Meiliu Lu Du Zhang Wing Kin Sung |
| Copyright Year | 2011 |
| Description | Author affiliation: School of Computing, National University of Singapore, Singapore (Wing Kin Sung) || Computer Science Department, California State University, Sacramento, USA (Malpani, R.; Meiliu Lu; Du Zhang) |
| Abstract | To gain insight into regulatory mechanisms underlying the transcription process of gene expressions, we need to understand the co-expressed gene sets under common regulatory mechanisms. Though computational methods have been developing to identify expression module, challenges still remain for cancer related gene expression profiling. In this paper, we have developed a method of data preprocessing and two different association rule mining approaches for discovering breast cancer regulatory mechanisms of gene module. Our data preprocessing task involved with two independent data sources: (a) a single breast cancer patient profile data file, (b) a candidate enhancer information data file. Using the integrated data, we also conducted four experiments of the association rule mining. |
| Starting Page | 154 |
| Ending Page | 159 |
| File Size | 360789 |
| Page Count | 6 |
| File Format | |
| ISBN | 9781457709647 |
| e-ISBN | 9781457709661 |
| e-ISBN | 9781457709654 |
| DOI | 10.1109/IRI.2011.6009538 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2011-08-03 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Association rules Breast cancer Gene expression Data preprocessing DNA Machine Learning Data mining Information Integration Association rule mining |
| Content Type | Text |
| Resource Type | Article |
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