NDLI: Estimating the stretching characteristics of fiber bundles in microscopic images

Content Provider	IEEE Xplore Digital Library
Author	Elbischger, P. Bischof, H. Holzapfel, G.
Copyright Year	2004
Description	Author affiliation: Inst. for Comput. Graphics & Vision, Graz Univ. of Technol., Austria (Elbischger, P.; Bischof, H.)
Abstract	Collagen fiber bundles are important constituent parts of biological soft tissues, such as tendons, blood vessels and skin. The single collagen fibers within a bundle have a certain crimp that determines the bundle's stretching characteristic, which is of particular interest in mechanobiology. A thorough understanding of the complex interrelations between mechanical factors and the associated biological responses may help to improve diagnostics, which allow disease and injury to be treated earlier. We present a method to obtain the relative stretching characteristics (RSC) of collagen (fibrous) bundles based on the analysis of microscopic tissue images. We show, how the orientation statistics of local orientations in a bundle can be directly related to the RSC. The von Mises distribution (VMD) - a circular probability distribution is used to describe the 2D orientation statistics. The k parameter of the VMD is used to obtain the mean stretching and the probability density function (PDF) of the bundles' RSC is identified.
Starting Page	546
Ending Page	549
File Size	381132
Page Count	4
File Format	PDF
ISBN	0769521282
ISSN	10514651
DOI	10.1109/ICPR.2004.1334587
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-08-26
Publisher Place	UK
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Microscopy Statistical distributions Biological tissues Tendons Blood vessels Biomedical imaging Skin Mechanical factors Diseases Injuries
Content Type	Text
Resource Type	Article
Subject	Computer Vision and Pattern Recognition

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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