NDLI: A PET prototype for in-beam monitoring of proton therapy

Content Provider	IEEE Xplore Digital Library
Author	Vecchio, S. Attanasi, F. Belcari, N. Camarda, M. Pablo Cirrone, G.A. Cuttone, G. Del Guerra, A. Di Rosa, F. Lanconelli, N. Moehrs, S. Rosso, V. Russo, G.
Copyright Year	2007
Description	Author affiliation: Univ. of Pisa, Pisa (Vecchio, S.; Attanasi, F.; Belcari, N.; Camarda, M.)
Abstract	The in-beam PET is a novel PET application to image the $beta^{+}$ activity induced in biological tissues by hadronic therapeutic beams. Thanks to the correlation existing between beam-delivered dose profiles and beam-induced activity profiles, in vivo information about the effective ion paths can be extracted from the in-beam PET image. In-situ measurements, immediately after patient irradiation, are recommended in order to exploit the maximum statistics, by detecting the contribution provided by short lived isotopes. A compact, dedicated tomograph should then be developed for such an application, so as to be used in the treatment room. We have realized a small PET prototype in order to demonstrate the feasibility of such technique for the monitoring of proton therapy of ocular tumors at the CATANA facility (Catania, Italy). The DoPET (dosimetry with a positron emission Tomograph) tomograph consists of two planar heads, with an active area of about 5 cm x 5 cm. Each head is made up of a squared position sensitive photomultiplier (Hamamatsu H8500) coupled to a matrix of the same size of LYSO scintillating crystals (2 mm times 2 mm times 18 mm pixel dimensions). Dedicated, compact electronic boards are used for the signal multiplexing, amplification and digitization. The distance between the pair can be set from 10 cm up to a maximum of about 20 cm. The validation of the prototype was performed using 62 MeV protons at the CATANA beam line and plastic phantoms. Different dose distributions have been delivered and a good correlation between the distal fall-off of the activity profiles and of the dose profiles was found, i.e., better than 2 mm along the beam direction.
Starting Page	1607
Ending Page	1611
File Size	946557
Page Count	5
File Format	PDF
ISBN	9781424409228
ISSN	10957863
DOI	10.1109/NSSMIC.2007.4437306
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-10-26
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Positron emission tomography Prototypes Monitoring Protons Medical treatment Head Biological tissues In vivo Data mining Statistics
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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