NDLI: A comparison of count rate performance for /sup 15/O-water blood flow studies in the CTI HR+ and Accel tomographs in 3D mode

Content Provider	IEEE Xplore Digital Library
Author	Spinks, T.J. Bloomfield, P.M.
Copyright Year	2003
Description	Author affiliation: Imaging Res. Solutions Ltd., Hammersmith Hosp., London, UK (Spinks, T.J.)
Abstract	The count rate performance of two commercial PET tomographs, the CTI HR+ (BGO) and Accel (LSO), is compared from simulations of blood flow studies. Data were derived from in vivo studies of blood flow (/sup 15/O-water) in the brain, heart and abdomen using the EXACT3D tomograph (6 rings of HR+ detector blocks). Noise-equivalent count (NEC) rate curves were simulated from these data for The HR+ and Accel using (a) standard pulse integration times and coincidence windows, (b) measured sensitivities and scatter fractions, and (c) adjustment of singles rates to reflect the different axial fields-of-view. The original administered doses for the EXACT3D studies were 163 MBq (brain), 92.5 MBq (heart) and 189 MBq (abdomen). These doses are constrained by the sensitivity of the EXACT3D (at least twice as high as standard commercial tomographs) and the count rate limit of the acquisition system. If the original (in vivo) EXACT3D doses are doubled to compensate for the lower sensitivity, the simulations show that peak NEC for the HR+ is still higher than or very close to that for the Accel in the three types of study. The superior count rate performance of the Accel gives improved NECs when dose is further increased. Thus the use of LSO detectors does not automatically confer advantages in count rate performance as this depends on the specific tomograph construction and the administered dose. These results reflect the lower intrinsic sensitivity of the Accel and its similar scatter fraction to the HR+ despite the higher light output.
Starting Page	1457
Ending Page	1460
File Size	368832
Page Count	4
File Format	PDF
ISBN	0780376366
DOI	10.1109/NSSMIC.2002.1239595
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-11-10
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	National electric code Brain modeling Blood flow In vivo Heart Abdomen Detectors Pulse measurements Light scattering Positron emission tomography
Content Type	Text
Resource Type	Article

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