NDLI: Quantification in positron emission mammography (PEM) with planar detectors: contrast resolution measurements using a custom breast phantom and novel spherical hot-spots

Content Provider	IEEE Xplore Digital Library
Author	Murthy, K. Jolly, D. Aznar, M. Thompson, C.J. Sciascia, P. Loutfi, A. Lisbona, R. Gagnon, J.H.
Copyright Year	1999
Description	Author affiliation: Neurological Inst., Montreal, Que., Canada (Murthy, K.)
Abstract	The authors have previously demonstrated that their Positron Emission Mammography-1 (PEM-1) system can successfully defect small (<2 cm diameter) tumors. Images in the current system are judged qualitatively for the presence of focal uptake of /sup 18/F-FDG. The authors are presently taking steps toward quantifying the emission images. To this end, they have constructed a breast phantom and developed a novel technique for fabricating very small wall-less radioactive hot-spots. The hot-spots are made by adding /sup 18/F-FDG to a 25 mg/cc solution of Agarose in water. The heated solution is poured into spherical molds which are separated upon congealing to yield robust wall-less radioactive hot-spots. The hot-spots were found to be uniform to within 1-5 parts in 100. Less than 0.1% of the total hot-spot activity leaked into the background in 30 minutes. Contrast resolution experiments have been performed with 12 mm and 16 mm diameter hot-spots in the breast phantom containing water with various amounts of background activity. In both cases, the observed contrast values agree well with the ideal values. In the case of the 12 mm hot-spot with a 350-650 keV energy window, mean image contrast was 86/spl plusmn/4% of ideal contrast. The image contrast for 12 mm hot-spot improved by 40% and the number of detected events decreases by 35% when the low energy threshold was increased from 300 keV to 450 keV. Activity uptake in the heart was found to have negligible effect on the contrast resolution.
Starting Page	1516
Ending Page	1520
File Size	480238
Page Count	5
File Format	PDF
ISBN	0780350219
ISSN	10823654
DOI	10.1109/NSSMIC.1998.773832
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1998-11-08
Publisher Place	Canada
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Radioactive decay Mammography Detectors Instruments Imaging phantoms Breast neoplasms Medical treatment Spatial resolution Energy resolution Image resolution
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Quantification in positron emission mammography (PEM) with planar detectors: contrast resolution measurements using a custom breast phantom and novel spherical hot-spots

Evaluation of a high resolution positron emission tomography (PET) scanner for positron emission mammography (PEM)

Positron emission mammography with multiple angle acquisition

Imaging performance of PEM-1: a high resolution system for positron emission mammography

An overview of the Clear-PEM breast imaging scanner

A positron emission mammography system based on 4 mm straw detectors

Fully digital trigger and pre-processing electronics for planar positron emission mammography (PEM) scanners

Feasibility study of using PEImager scanner for positron emission mammography

Positron emission mammography (PEM): a promising technique for detecting breast cancer

Quantification in positron emission mammography (PEM) with planar detectors: contrast resolution measurements using a custom breast phantom and novel spherical hot-spots

Similar Documents

Quantification in positron emission mammography (PEM) with planar detectors: contrast resolution measurements using a custom breast phantom and novel spherical hot-spots

Evaluation of a high resolution positron emission tomography (PET) scanner for positron emission mammography (PEM)

Positron emission mammography with multiple angle acquisition

Imaging performance of PEM-1: a high resolution system for positron emission mammography

An overview of the Clear-PEM breast imaging scanner

A positron emission mammography system based on 4 mm straw detectors

Fully digital trigger and pre-processing electronics for planar positron emission mammography (PEM) scanners

Feasibility study of using PEImager scanner for positron emission mammography

Positron emission mammography (PEM): a promising technique for detecting breast cancer

Quantification in positron emission mammography (PEM) with planar detectors: contrast resolution measurements using a custom breast phantom and novel spherical hot-spots