NDLI: Differentiating between patients with vasovagal syncope using the analysis of heart rate variability during head-up tilt test

Content Provider	IEEE Xplore Digital Library
Author	Khodor, N. Amoud, H. Khalil, M. Matelot, D. Hernandez, A. Carrault, G. Carre, F.
Copyright Year	2013
Description	Author affiliation: Azm platform for Res. in Biotechnol. & its Applic., Electron. Team, Lebanese Univ., Tripoli, Lebanon (Khodor, N.; Amoud, H.; Khalil, M.) \|\| Lab. of Signal & Image Process., Univ. of Rennes 1, Rennes, France (Khodor, N.; Matelot, D.; Hernandez, A.; Carrault, G.; Carre, F.)
Abstract	The aim of this paper is to improve the physiological understanding in order to differentiate between the two types of vasovagal syncope by performing a Head-up Tilt Test. The Head-up Tilt Test is a well known procedure to reproduce vasovagal syncope, patients who had syncope during the test show different orthostatic response depending on they are cardioinhibitory or vasodepressor patients which can be explain by different pathogeneses, although existing knowledge of the autonomic balance in patients with positive response is still not completely clear. The Electrocardiogram signal from 20 patients, 12 cardioinhibitory and 8 vasodepressor were analyzed with the validated software Segmenta (Laboratory of Signal and Image Processing, Rennes) to extract classical heart rate variability parameters then comparison were made within and between group for 5 minutes of resting, the first 5 minutes of the tilt test and the last 5 minutes before syncope. The Results show that Cardioinhibitory patients had higher low frequency parameter in the last 5 minutes before syncope than vasodepressor patients (p<;0.05), using Principal Component Analysis, differentiating between cardioinhibitor and vasodepressor group can be done in the 5 minutes of resting and the last 5 minutes before syncope. This study suggests a lack of sympatho-vagal balance activation in subjects with vasovagal syncope which can be explained by attenuation in cardiac rhythm regulation and predominance sympathetic activity for cardioinhibitory patients. In addition we demonstrated that by using one parameter (Low Frequency), we can distinguish between the two types before five minutes of syncope but by a combination of multiple parameters using principal component analysis we can differentiate the two groups from the five minutes of supine position.
Sponsorship	IEEE United Arab Emirates Sect.
Starting Page	1
Ending Page	4
File Size	190029
Page Count	4
File Format	PDF
ISBN	9781467328203
e-ISBN	9781467328210
DOI	10.1109/ICCSPA.2013.6487260
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-02-12
Publisher Place	United Arab Emirates
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Time series analysis Syncope Head-up tilt test Electrocardiography Educational institutions Heart rate variability Standards Spectral analysis Principal component analysis
Content Type	Text
Resource Type	Article

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