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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | McCabe, J.T. Moratz, C. Yunbo Liu Egan, R. HuaZhen Chen Jiong Liu Budinich, C.S. Burton, E.E. Danquah, J.K. Myers, M.R. |
| Copyright Year | 2010 |
| Description | Author affiliation: Food and Drug Administration, Silver Spring, MD 20993 (Yunbo Liu; Myers, M.R.) || Uniformed Services University of the Health Sciences and the Center for Neuroscience and Regenerative Medicine, Bethesda, MD 20814 (McCabe, J.T.; Moratz, C.; Egan, R.; HuaZhen Chen; Jiong Liu; Budinich, C.S.; Burton, E.E.; Danquah, J.K.) |
| Abstract | In present war time conditions, traumatic brain injury (TBI) has moved to the forefront as a “signature injury.” In terms of prevalence and understanding the biological mechanisms that underlie the injury, blast-induced TBI — particularly in “mild” cases-has proven to be a significant challenge for military medicine. Basic research that employs animal models of TBI is a key element for furthering our understanding of the biological consequences of blast-related TBI and for the development of therapeutic approaches. This paper outlines the currently available prototypes for the study of TBI, particularly in rodent models, and how the most widely used approaches for modeling TBI can contribute to understanding the mechanisms of injury. |
| Starting Page | 1 |
| Ending Page | 4 |
| File Size | 183178 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424467136 |
| e-ISBN | 9781424467143 |
| DOI | 10.1109/BSEC.2010.5510803 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2010-05-25 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Head Neuroscience Animals Biological system modeling Rodents Prototypes Brain modeling Cranial pressure Explosives Brain injuries |
| Content Type | Text |
| Resource Type | Article |
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