NDLI: Smart Targeted Drug Delivery System Using Swarm Based Drug Loaded Nano Particles Simulation

Content Provider	IEEE Xplore Digital Library
Author	Hassan, S. Jungown Yoon
Copyright Year	2013
Description	Author affiliation: Sch. of Mech. & Aerosp. Eng., Gyeongsang Nat. Univ., Jinju, South Korea (Hassan, S.; Jungown Yoon)
Abstract	This paper presents the target path planning biomedical application for the swarm of drug loaded nano carriers in a complex three dimensional virtual environment. To improve the effectiveness of drug a smart targeted drug delivery system is designed in a virtual environment that is capable of targeting the swarm of nano particles to specific disease site. Based on the virtual environment the parametric study of obstacle avoidance, optimization for shortest path and the required attractive force to target the nano particles in a disease affected site are investigated. Artificial potential field is used to generate magnetic attractive and repulsive forces to plan obstacle free path from initial to targeted position. Particle swarm optimization (PSO) is applied to optimize the path for drug loaded particles swarm. The simulation results showed that the proposed system is closer to real-time (online) and converges towards optimal path with high success rate.
Sponsorship	IEEE Region 10 - Asia Pacific
Starting Page	177
Ending Page	181
File Size	396647
Page Count	5
File Format	PDF
ISBN	9781467356534
ISSN	21660662
DOI	10.1109/ISMS.2013.105
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-01-29
Publisher Place	Thailand
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Drugs Targeted drug delivery Magnetic resonance imaging Force Nano particles Path planning Nano Swarm Particle swarm optimization PSO Optimization
Content Type	Text
Resource Type	Article

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