NDLI: Multi-bifurcation flow analysis on 2D human respiratory airway system

Content Provider	IEEE Xplore Digital Library
Author	Ngali, Mohd Zamani Osman, Kahar Mohd Hazmil Syahidy Abdol Azis
Copyright Year	2010
Description	Author affiliation: Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310, Skudai, Johor, Malaysia (Osman, Kahar; Mohd Hazmil Syahidy Abdol Azis) \|\| Faculty of Mechanical and Manufacturing Engineering, Universiti Tun Hussein Onn Malaysia, 86400, Batu Pahat, Johor, Malaysia (Ngali, Mohd Zamani)
Abstract	Drug inhalation through respiratory airway is the principal method in attaining therapeutic effect for many lung diseases. The multi-bifurcating flow structure acquires deep understanding on the flow driven transportation. This work employs Navier-Stokes equation with Splitting Method numerical flow solver utilizing domain characterization technique. Various breathing conditions are commenced to Weibel's morphometric lung model from fifth to seventh generations of human respiratory system. Velocity distributions, vortex formations and cross-sectional velocity profiles are considered for Reynolds number ranging from resting to moderate exercise breathing. Flow with low Reynolds number retains its symmetric cross-sectional velocity profile across each bifurcation region while higher Reynolds number shows the other way. Drug delivery efficacy is higher with slower inhalation while hard breathing stimulates vortex formations and disturbs drug distributions right through the multi-bifurcation structure.
Starting Page	1260
Ending Page	1265
File Size	2431510
Page Count	6
File Format	PDF
ISBN	9781424489879
e-ISBN	9781424489862
DOI	10.1109/CSSR.2010.5773730
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-12-05
Publisher Place	Malaysia
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Humans Navier-Stokes Drug delivery Splitting method Respiratory system Multi-bifurcation
Content Type	Text
Resource Type	Article

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