NDLI: The electrocardiogram restitution portrait quantifying dynamical electrical instability in young myocardium

Content Provider	IEEE Xplore Digital Library
Author	Bell, J.A. Rouze, N.C. Krassowska, W. Idriss, S.F.
Copyright Year	2007
Description	Author affiliation: Duke Univ., Durham, NC (Bell, J.A.; Rouze, N.C.; Krassowska, W.; Idriss, S.F.)
Abstract	Novel methods need to be developed to detect electrical instability in children. The dynamical properties of action potential restitution play an important role in the development of instability leading to arrhythmias. A new method, the Restitution Portrait (RP), was developed to visualize and quantify these properties at the action potential level. Here, we apply the RP method using the activation-recovery interval (ARI) from the ECG to detect, in vitro, repolarization abnormalities in neonatal and preadolescent rabbit myocardium with drug-induced Long QT Syndrome (LQTS Type 1 or Type 2). The ECG was recorded during programmed endocardial pacing to record the RP. The ECG RP demonstrated significant changes in dynamical restitution components during drug-induced LQTS compared to baseline. This study shows that the ECG RP may be an important noninvasive diagnostic tool for detecting electrical instability in the young.
Starting Page	789
Ending Page	792
File Size	1961984
Page Count	4
File Format	PDF
ISBN	9781424425334
ISSN	02766547
DOI	10.1109/CIC.2007.4745604
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2007-09-30
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Computers in Cardiology(CinC)
Subject Keyword	Myocardium Steady-state Electrocardiography Pediatrics Transient response Computer displays Protocols Medical treatment Heart rate History
Content Type	Text
Resource Type	Article

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The Electrocardiogram Restitution Portrait Quantifying Dynamical Electrical Instability in Young Myocardium

The Electrocardiogram Restitution Portrait Quantifying Dynamical Electrical Instability in Young

Analysis of transient heart rate response to the active orthostatic maneuver

Evaluation of restitution slopes using a quasi-stationary exercise protocol

Iterative restitution effects from heart rate variability

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The electrocardiogram restitution portrait quantifying dynamical electrical instability in young myocardium

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The Electrocardiogram Restitution Portrait Quantifying Dynamical Electrical Instability in Young Myocardium

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Analysis of transient heart rate response to the active orthostatic maneuver

Evaluation of restitution slopes using a quasi-stationary exercise protocol

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