NDLI: On the use of st-segment shifts and mathematical models for identifying ischemic heart disease

Content Provider	IEEE Xplore Digital Library
Author	Nielsen, B.F. Lysaker, M. Tarrou, C. MacLachlan, M.C. Abildgaard, A. Tveito, A.
Copyright Year	2005
Description	Author affiliation: Simula Res. Lab., Oslo (Nielsen, B.F.; Lysaker, M.; Tarrou, C.; MacLachlan, M.C.)
Abstract	It is well known that myocardial ischemia can be observed as a shift in the ST segment of an ECG recording. In this paper we will discuss how ST-segment shift, along with advanced mathematical models, can be used to compute the size and location of the ischemic region-an inverse problem. Traditionally, the inverse approach to localizing ischemia has been based on the calculation of epicardial potentials. We present an alternative approach where the location and size of the ischemic region are computed directly by solving a parameter identification problem based on a level set framework and partial differential equations (PDEs). More precisely, the ischemic region is identified by minimizing an objective function measuring the difference between the recorded and simulated ECG signals. Our results show, at least for synthetic ECG data, that values of ST shift recorded at the body surface are capable of identifying the position and (roughly) the size of the ischemia
Starting Page	1005
Ending Page	1008
File Size	158409
Page Count	4
File Format	PDF
ISBN	0780393376
DOI	10.1109/CIC.2005.1588280
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2005-09-25
Publisher Place	France
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Mathematical model Cardiac disease Ischemic pain Electrocardiography Myocardium Inverse problems Parameter estimation Level set Partial differential equations Computational modeling
Content Type	Text
Resource Type	Article

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