NDLI: Assessment of an automatic determination of left ventricular dP/dt from Doppler spectra of mitral regurgitation

Content Provider	IEEE Xplore Digital Library
Author	Carlier, S. Verdonck, P. Dimmer, C. Vandenbossche, J.L.
Copyright Year	1995
Description	Author affiliation: Dept. of Cardiology, Univ. Hospital Saint-Pierre, Brussels, Belgium (Carlier, S.)
Abstract	Left ventricular (LV) pressure can be derived noninvasively from the continuous wave Doppler spectra of a mitral regurgitation using the simplified Bernoulli equation. The peak of its first derivative (dP/dt) reflects LV systolic function. Presently, it can be computed on profiles digitised tediously by hand tracings. This paper describes an evaluation of peak dP/dt based on the automatic determination of the contour of regurgitant velocity profiles after digitisation of raw Doppler signals with an A/D board and a PC. This method has been validated in vitro on a pulse duplicator in which a leaking mitral prosthesis was studied under several hemodynamic conditions. The Doppler derived peak dP/dt was well correlated (r/sup 2/=0.9, SEE=251 mmHg) with the measured one. Also recordings on patients showed a good correlation with the mean (1-3 m/s) dP/dt (r/sup 2/=0.7. SEE=365 mmHg), showing a systematic underestimation (199/spl plusmn/176 mmHg). In conclusion, our method is an easy and reliable tool to measure peak LV dP/dt.
Starting Page	321
Ending Page	324
File Size	377758
Page Count	4
File Format	PDF
ISBN	0780330536
DOI	10.1109/CIC.1995.482637
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1995-09-10
Publisher Place	Austria
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	In vitro Cardiology Equations Pressure measurement Filters Hospitals Laboratories Hemodynamics Catheterization Echocardiography
Content Type	Text
Resource Type	Article

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