NDLI: Impaired baroreflex sensitivity and nocturnal periodic breathing in patients with chronic heart failure

Content Provider	IEEE Xplore Digital Library
Author	Lanfranchi, P. Braghiroli, A. Colombo, R. Mazzuero, G. Giannuzzi, P.
Copyright Year	1995
Description	Author affiliation: Fondazione Salvatore Maugeri, IRCCS, Veruno, Italy (Lanfranchi, P.)
Abstract	Nocturnal periodic breathing is a common finding in severe chronic heart failure (CHF). Patients (pts) with left ventricular dysfunction can exhibit impairment of baroreflex sensitivity (BRS) or heart rare variability (HRV). We studied 48 pts aged 57/spl plusmn/8 years with CHF in stable phase (EF=23/spl plusmn/6%). All pts underwent a sleep study to assess the occurrence of periodic breathing, and a phenylephrine test to evaluate BRS; 36 patients had also a 24 hour ambulatory electrocardiogram recording to measure HRV. Nocturnal periodic breathing was recorded in 75% of patients, BRS was markedly depressed in 60% of patients, HRV was reduced in 58% of patients. Significant correlations were found between %PB and left ventricle EF (p=0.016), BRS (p=0.0002), HRV (p=0.0001), and nocturnal oxygen desaturation (p=0.0001). Nocturnal periodic breathing is frequently associated with abnormal autonomic control of cardiac function in patients suffering from chronic heart failure.
Starting Page	309
Ending Page	311
File Size	206154
Page Count	3
File Format	PDF
ISBN	0780330536
DOI	10.1109/CIC.1995.482634
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	1995-09-10
Publisher Place	Austria
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Baroreflex Heart rate variability Cardiology Neural networks Cardiac disease Cardiovascular diseases Sleep Testing Heart rate Aging
Content Type	Text
Resource Type	Article

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